| http://purl.uniprot.org/citations/12895422 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12895422 | http://www.w3.org/2000/01/rdf-schema#comment | "Ca2+ influx into presynaptic terminals via voltage-dependent Ca2+ channels triggers fast neurotransmitter release as well as different forms of synaptic plasticity. Using electrophysiological and genetic techniques we demonstrate that presynaptic Ca2+ entry through Cav2.3 subunits contributes to the induction of mossy fiber LTP and posttetanic potentiation by brief trains of presynaptic action potentials while they do not play a role in fast synaptic transmission, paired-pulse facilitation, or frequency facilitation. This functional specialization is most likely achieved by a localization remote from the release machinery and by a Cav2.3 channel-dependent facilitation of presynaptic Ca2+ influx. Thus, the presence of Cav2.3 channels boosts the accumulation of presynaptic Ca2+ triggering presynaptic LTP and posttetanic potentiation without affecting the low release probability that is a prerequisite for the enormous plasticity displayed by mossy fiber synapses."xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(03)00430-6"xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/author | "Dietrich D."xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/author | "Schneider T."xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/author | "Pereverzev A."xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/author | "Beck H."xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/author | "Kirschstein T."xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/author | "Kukley M."xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/author | "von der Brelie C."xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/pages | "483-496"xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/title | "Functional specialization of presynaptic Cav2.3 Ca2+ channels."xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://purl.uniprot.org/core/volume | "39"xsd:string |
| http://purl.uniprot.org/citations/12895422 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12895422 |
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