| http://purl.uniprot.org/citations/12897786 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12897786 | http://www.w3.org/2000/01/rdf-schema#comment | "The specification and differentiation of serotonergic (5-HT) neurons require both extrinsic signaling molecules and intrinsic transcription factors to work in concert or in cascade. Here we identify the genetic cascades that control the specification and differentiation of 5-HT neurons in mice. A major determinant in the cascades is an LIM homeodomain-containing gene, Lmx1b, which is required for the development of all 5-HT neurons in the central nervous system. Our results suggest that, during development of 5-HT neurons, Lmx1b is a critical intermediate factor that couples Nkx2-2-mediated early specification with Pet1-mediated terminal differentiation. Moreover, our data indicate that genetic cascades controlling the caudal and rostral 5-HT neurons are distinct, despite their shared components."xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn1104"xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/author | "Marklund U."xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/author | "Yin J."xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/author | "Johnson R.L."xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/author | "Yuan W."xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/author | "Chen Z.F."xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/author | "Ding Y.Q."xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/author | "Ericson J."xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/author | "Deneris E."xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/author | "Wegman L."xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/name | "Nat Neurosci"xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/pages | "933-938"xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/title | "Lmx1b is essential for the development of serotonergic neurons."xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://purl.uniprot.org/core/volume | "6"xsd:string |
| http://purl.uniprot.org/citations/12897786 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12897786 |
| http://purl.uniprot.org/citations/12897786 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12897786 |
| http://purl.uniprot.org/uniprot/O88609#attribution-D5699E4AEEA57A45945539DF80FB69D9 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12897786 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J0I7-mappedCitation-12897786 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12897786 |
| http://purl.uniprot.org/uniprot/#_E0CXR7-mappedCitation-12897786 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12897786 |
| http://purl.uniprot.org/uniprot/#_A0A6I8MWW7-mappedCitation-12897786 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12897786 |
| http://purl.uniprot.org/uniprot/#_B3GAP8-mappedCitation-12897786 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12897786 |
| http://purl.uniprot.org/uniprot/#_O88609-mappedCitation-12897786 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12897786 |