RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/12910265http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12910265http://www.w3.org/2000/01/rdf-schema#comment"The major histocompatibility complex (MHC) class II transactivator (CIITA) is the 'master coactivator' of MHC class II genes. To identify new targets of CIITA, we analyzed cDNA microarrays of dendritic cells (DCs) from CIITA-deficient, MHC class II-deficient and control mice. We found the semaphorin receptor plexin-A1 was expressed in DCs, but not in other immune cells, and was strongly induced by CIITA. RNA interference by short hairpin RNA specific for plexin-A1, but not a single-nucleotide mutant, greatly reduced plexin-A1 expression and T cell stimulation by protein- or peptide-antigen-pulsed DCs.Plexin-A1 is not required for peptide binding to MHC. These data indicate involvement of plexin-A1 in T cell-DC interactions but not antigen processing or binding."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.org/dc/terms/identifier"doi:10.1038/ni960"xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"Brickey W.J."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"Liu Y."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"Li P."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"Ting J.P."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"Zheng P."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"Taxman D.J."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"Blum J.S."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"Wong A.W."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"Reed W."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"Gao J.X."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"McKinnon K.P."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/author"van Deventer H.W."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/name"Nat Immunol"xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/pages"891-898"xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/title"CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions."xsd:string
http://purl.uniprot.org/citations/12910265http://purl.uniprot.org/core/volume"4"xsd:string
http://purl.uniprot.org/citations/12910265http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12910265
http://purl.uniprot.org/citations/12910265http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12910265
http://purl.uniprot.org/uniprot/#_A0A0N4SUU1-mappedCitation-12910265http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12910265
http://purl.uniprot.org/uniprot/#_A0A0N4SW74-mappedCitation-12910265http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12910265
http://purl.uniprot.org/uniprot/#_A0A1D5RM20-mappedCitation-12910265http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12910265