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http://purl.uniprot.org/citations/12913148http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12913148http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12913148http://www.w3.org/2000/01/rdf-schema#comment"Exportin-t was first identified in humans as a protein that mediates the export of tRNAs from the nucleus to the cytoplasm. Mutations in Los1p, the Saccharomyces cerevisiae exportin-t homolog, result in nuclear accumulation of tRNAs. Because no exportin-t mutants have been reported in multicellular organisms, the developmental functions of exportin-t have not been determined. Here, we report the isolation and characterization of two Arabidopsis exportin-t mutants, paused-5 and paused-6. The mutant phenotypes indicate that exportin-t acts pleiotropically in plant development. In particular, paused-5 and paused-6 result in delayed leaf formation during vegetative development. The two paused mutations also cause the transformation of reproductive organs into perianth organs in the hua1-1 hua2-1 background, which is partially defective in reproductive organ identity specification. The floral phenotypes of hua1-1 hua2-1 paused mutants resemble those of mutations in the floral homeotic gene AGAMOUS. Moreover, paused-5 enhances the mutant phenotypes of two floral meristem identity genes, LEAFY and APETALA1. The developmental defects caused by paused mutations confirm the important roles of exportin-t in gene expression in multicellular organisms. In addition, a paused null allele, paused-6, is still viable, suggesting the presence of redundant tRNA export pathway(s) in Arabidopsis."xsd:string
http://purl.uniprot.org/citations/12913148http://purl.org/dc/terms/identifier"doi:10.1104/pp.103.023291"xsd:string
http://purl.uniprot.org/citations/12913148http://purl.org/dc/terms/identifier"doi:10.1104/pp.103.023291"xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/author"Chen X."xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/author"Chen X."xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/author"Li J."xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/author"Li J."xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/name"Plant Physiol."xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/name"Plant Physiol."xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/pages"1913-1924"xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/pages"1913-1924"xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/title"PAUSED, a putative exportin-t, acts pleiotropically in Arabidopsis development but is dispensable for viability."xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/title"PAUSED, a putative exportin-t, acts pleiotropically in Arabidopsis development but is dispensable for viability."xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/volume"132"xsd:string
http://purl.uniprot.org/citations/12913148http://purl.uniprot.org/core/volume"132"xsd:string
http://purl.uniprot.org/citations/12913148http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12913148
http://purl.uniprot.org/citations/12913148http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12913148
http://purl.uniprot.org/citations/12913148http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12913148
http://purl.uniprot.org/citations/12913148http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12913148
http://purl.uniprot.org/embl-cds/AAP37047.1http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/12913148
http://purl.uniprot.org/uniprot/Q7PC79http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/12913148