http://purl.uniprot.org/citations/12913156 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12913156 | http://www.w3.org/2000/01/rdf-schema#comment | "The phytohormone cytokinin is an important regulator of plant growth and development; however, relatively few genes that mediate cytokinin responses have been identified. Genome-wide analyses of Arabidopsis seedlings using the approximately 8,300-element Affymetrix Arabidopsis GeneChips (Affymetrix, Santa Clara, CA) to examine cytokinin-responsive genes were conducted, revealing at least 30 genes whose steady-state level of mRNA was elevated and at least 40 that were down-regulated at multiple time points after application of cytokinin. The cytokinin up-regulated genes include the type-A Arabidopsis response regulators (ARRs), which had been shown previously to be cytokinin primary response genes, cytokinin oxidase, which encodes an enzyme that degrades cytokinins, and several transcription factors. Cytokinin down-regulated genes include several peroxidases and kinases and an E3 ubiquitin ligase. We identified a common sequence motif enriched in the upstream regions of the most consistently cytokinin up-regulated genes. This motif is highly similar to the optimal DNA-binding sites for ARR1/ARR2, type-B ARRs that have been implicated in the transcriptional elevation of the type-A ARRs. Additionally, genome-wide analyses of cytokinin receptor mutants (wol/cre1) revealed large-scale changes in gene expression, including down-regulation of the type-A ARRs and several meristem and cell cycle genes, such as CycD3. Mutations in CRE1 reduced but did not eliminate the effect of cytokinin on gene expression for a subset of cytokinin-responsive genes and had little or no effect on others, suggesting functional redundancy among the cytokinin receptors."xsd:string |
http://purl.uniprot.org/citations/12913156 | http://purl.org/dc/terms/identifier | "doi:10.1104/pp.103.021436"xsd:string |
http://purl.uniprot.org/citations/12913156 | http://purl.uniprot.org/core/author | "Kieber J.J."xsd:string |
http://purl.uniprot.org/citations/12913156 | http://purl.uniprot.org/core/author | "Rashotte A.M."xsd:string |
http://purl.uniprot.org/citations/12913156 | http://purl.uniprot.org/core/author | "Carson S.D."xsd:string |
http://purl.uniprot.org/citations/12913156 | http://purl.uniprot.org/core/author | "To J.P."xsd:string |
http://purl.uniprot.org/citations/12913156 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12913156 | http://purl.uniprot.org/core/name | "Plant Physiol"xsd:string |
http://purl.uniprot.org/citations/12913156 | http://purl.uniprot.org/core/pages | "1998-2011"xsd:string |
http://purl.uniprot.org/citations/12913156 | http://purl.uniprot.org/core/title | "Expression profiling of cytokinin action in Arabidopsis."xsd:string |
http://purl.uniprot.org/citations/12913156 | http://purl.uniprot.org/core/volume | "132"xsd:string |
http://purl.uniprot.org/citations/12913156 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12913156 |
http://purl.uniprot.org/citations/12913156 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12913156 |
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http://purl.uniprot.org/uniprot/#_A0A178VNC5-mappedCitation-12913156 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12913156 |
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