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http://purl.uniprot.org/citations/12915227 | http://www.w3.org/2000/01/rdf-schema#comment | "The roX1 and roX2 genes of Drosophila produce non-coding transcripts that localize to the X-chromosome. In spite of their lack of sequence similarity, they are redundant components of an RNA/protein complex that up-regulates the male X-chromosome, contributing to the equalization of X-linked gene expression between males and females. roX1 is detected at 2 h AEL, prior to formation of the complex, and is present in both sexes. Maternally provided MLE (Maleless) is required for roX1 stability. By contrast, roX2 is male-specific and is first observed at 6 h. Either roX transcript can support X-localization of the complex, but localization is delayed in roX1 mutants until roX2 expression. These results support a model for the ordered assembly of the complex in embryos."xsd:string |
http://purl.uniprot.org/citations/12915227 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0925-4773(03)00157-6"xsd:string |
http://purl.uniprot.org/citations/12915227 | http://purl.uniprot.org/core/author | "Meller V.H."xsd:string |
http://purl.uniprot.org/citations/12915227 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12915227 | http://purl.uniprot.org/core/name | "Mech Dev"xsd:string |
http://purl.uniprot.org/citations/12915227 | http://purl.uniprot.org/core/pages | "759-767"xsd:string |
http://purl.uniprot.org/citations/12915227 | http://purl.uniprot.org/core/title | "Initiation of dosage compensation in Drosophila embryos depends on expression of the roX RNAs."xsd:string |
http://purl.uniprot.org/citations/12915227 | http://purl.uniprot.org/core/volume | "120"xsd:string |
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