| http://purl.uniprot.org/citations/12917799 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12917799 | http://www.w3.org/2000/01/rdf-schema#comment | "We studied HLA DQB1 allele frequencies and the relative risk (RR) of various genotypes in 72 type 1 diabetic patients and 40 control individuals in Uruguay. This is a tri-racial (Caucasian, Black and Indo-American) mixed population. The products of the polymerase chain reaction amplifications were hybridized with oligonucleotides by allele-specific oligonucleotide reverse or dot blot methods. Significant differences between these two groups were observed only for allele DQB1*0302 (35%, RR = 7.34, P<0.001). The frequency of the alleles carrying a non-aspartic acid residue at position 57 was significantly higher in the diabetic patients (85 vs 53%, P<0.001). In contrast, the frequency of Asp alleles was negatively associated with type 1 diabetes (RR = 0.20, P<0.001). The genotype DQB1*0302/DQB1*0201 (33%, RR = 5.41, P<0.05) was positively associated with this disease. The genotype frequencies associated with type 1 diabetes in our population were significantly different from what is known for Caucasian and Black populations as well as compared with another admixed population, from Chile."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/author | "Jorge A.M."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/author | "Mimbacas A."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/author | "Hidalgo P.C."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/author | "Cardoso H."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/author | "Gallino J.P."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/author | "Perez-Bravo F."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/author | "Gasagoite J."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/author | "Grignola R."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/author | "Javiel G."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/author | "Pisciottano C."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/name | "Genet Mol Res"xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/pages | "29-35"xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/title | "Association between diabetes type 1 and DQB1 alleles in a case-control study conducted in Montevideo, Uruguay."xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://purl.uniprot.org/core/volume | "2"xsd:string |
| http://purl.uniprot.org/citations/12917799 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12917799 |
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