| http://purl.uniprot.org/citations/12940997 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12940997 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12940997 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
| http://purl.uniprot.org/citations/12940997 | http://www.w3.org/2000/01/rdf-schema#comment | "SpoIVB is the critical determinant for intercompartmental signalling of pro-sigmaK processing during sporulation in Bacillus subtilis. We show here that the SpoIVB serine peptidase can cleave the SpoIVFA protein, which is one component of the pro-sigmaK processing complex. SpoIVFA has been shown elsewhere (Rudner, D.Z., and Losick, R., 2002, Genes Dev 16: 1007-1018) to tether BofA and SpoIVFB in a membrane-embedded heteroligomeric complex in which BofA directly inhibits the activity of SpoIVFB. Cleavage of SpoIVFA would provide the necessary signal to dissolve this complex and release BofA-mediated inhibition on the zinc metalloprotease, SpoIVFB, that is responsible for cleaving pro-sigmaK to its mature form. We also show that the SpoIVB PDZ domain is required for self-recognition and trans cleavage of SpoIVB and is probably also used to target an internal motif within the C-terminal region of SpoIVFA exposed in the space between the inner and outer forespore membranes. This work reveals the mechanism of intercompartmental signalling and provides a unified model as to how sigmaK-directed gene expression in the mother cell is co-ordinated with events in the forespore chamber."xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1365-2958.2003.03651.x"xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1365-2958.2003.03651.x"xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/author | "Cutting S.M."xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/author | "Cutting S.M."xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/author | "Dong T.C."xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/author | "Dong T.C."xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/pages | "1425-1434"xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/pages | "1425-1434"xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/title | "SpoIVB-mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of Pro-sigmaK in Bacillus subtilis."xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/title | "SpoIVB-mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of Pro-sigmaK in Bacillus subtilis."xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/volume | "49"xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://purl.uniprot.org/core/volume | "49"xsd:string |
| http://purl.uniprot.org/citations/12940997 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12940997 |
| http://purl.uniprot.org/citations/12940997 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12940997 |
| http://purl.uniprot.org/citations/12940997 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12940997 |
| http://purl.uniprot.org/citations/12940997 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12940997 |
| http://purl.uniprot.org/citations/12940997 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12940997 |