| http://purl.uniprot.org/citations/12952905 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12952905 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12952905 | http://www.w3.org/2000/01/rdf-schema#comment | "The van gogh (vgo) mutant in zebrafish is characterized by defects in the ear, pharyngeal arches and associated structures such as the thymus. We show that vgo is caused by a mutation in tbx1, a member of the large family of T-box genes. tbx1 has been recently suggested to be a major contributor to the cardiovascular defects in DiGeorge deletion syndrome (DGS) in humans, a syndrome in which several neural crest derivatives are affected in the pharyngeal arches. Using cell transplantation studies, we demonstrate that vgo/tbx1 acts cell autonomously in the pharyngeal mesendoderm and influences the development of neural crest-derived cartilages secondarily. Furthermore, we provide evidence for regulatory interactions between vgo/tbx1 and edn1 and hand2, genes that are implicated in the control of pharyngeal arch development and in the etiology of DGS."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.00704"xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.00704"xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Nair S."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Nair S."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Zhou Y."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Zhou Y."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Geisler R."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Geisler R."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Rauch G.J."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Zon L.I."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Zon L.I."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Dawid I.B."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Dawid I.B."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Ahn D.-G."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Ahn D.-G."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Ahn D.G."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Rauch G.-J."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Rauch G.-J."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Haffter P."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Haffter P."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Ho R.K."xsd:string |
| http://purl.uniprot.org/citations/12952905 | http://purl.uniprot.org/core/author | "Ho R.K."xsd:string |