| http://purl.uniprot.org/citations/12953064 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12953064 | http://www.w3.org/2000/01/rdf-schema#comment | "Previously we have shown that overexpression of the heterodimeric E2Fa-DPa transcription factor in Arabidopsis thaliana results in ectopic cell division, increased endoreduplication, and an early arrest in development. To gain a better insight into the phenotypic behavior of E2Fa-DPa transgenic plants and to identify E2Fa-DPa target genes, a transcriptomic microarray analysis was performed. Out of 4,390 unique genes, a total of 188 had a twofold or more up-(84) or down-regulated (104) expression level in E2Fa-DPa transgenic plants compared to wild-type lines. Detailed promoter analysis allowed the identification of novel E2Fa-DPa target genes, mainly involved in DNA replication. Secondarily induced genes encoded proteins involved in cell wall biosynthesis, transcription and signal transduction or had an unknown function. A large number of metabolic genes were modified as well, among which, surprisingly, many genes were involved in nitrate assimilation. Our data suggest that the growth arrest observed upon E2Fa-DPa overexpression results at least partly from a nitrogen drain to the nucleotide synthesis pathway, causing decreased synthesis of other nitrogen compounds, such as amino acids and storage proteins."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.org/dc/terms/identifier | "doi:10.1242/jcs.00715"xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/author | "Inze D."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/author | "Van de Peer Y."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/author | "Rombauts S."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/author | "Van Hummelen P."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/author | "Vuylsteke M."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/author | "De Veylder L."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/author | "Maes S."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/author | "Vlieghe K."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/author | "Ormenese S."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/author | "Florquin K."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/name | "J Cell Sci"xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/pages | "4249-4259"xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/title | "Microarray analysis of E2Fa-DPa-overexpressing plants uncovers a cross-talking genetic network between DNA replication and nitrogen assimilation."xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://purl.uniprot.org/core/volume | "116"xsd:string |
| http://purl.uniprot.org/citations/12953064 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12953064 |
| http://purl.uniprot.org/citations/12953064 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12953064 |
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| http://purl.uniprot.org/uniprot/#_F4K051-mappedCitation-12953064 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12953064 |
| http://purl.uniprot.org/uniprot/#_F4K3I6-mappedCitation-12953064 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12953064 |
| http://purl.uniprot.org/uniprot/#_F4K470-mappedCitation-12953064 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12953064 |
| http://purl.uniprot.org/uniprot/#_F4K627-mappedCitation-12953064 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12953064 |