| http://purl.uniprot.org/citations/12964117 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12964117 | http://www.w3.org/2000/01/rdf-schema#comment | "The human leukocyte antigen (HLA)-B22 serogroup--which consists of the alleles B*54, B*55, and B*56--has been associated with rapidly progressive disease in white patients with human immunodeficiency virus (HIV) infection. Subjects from 3 cohorts of men who have sex with men (N=671), all of whom experienced HIV-1 seroconversion at roughly the same time, were molecularly typed at HLA-A, -B, and -C loci. Mean HIV RNA loads during early HIV infection were higher in B22-positive men than in B22-negative men (difference, 0.481 log(10) HIV RNA copies/mL; 95% confidence interval [CI], 0.156-0.806 log(10) HIV RNA copies/mL; P=.004). Independent of accepted markers of progression, time-to-AIDS was shorter in B22-positive seroconverters (adjusted hazard ratio, 1.98; 95% CI, 1.27-3.10; P=.003). White B22 serogroup alleles (B*55 and *56) appear to predispose to unfavorable outcome of HIV infection as strongly as some or all B*35 and B*53 alleles. This finding may have greater implications for Asians, because the marker frequency for B22 is higher among Asians than among whites (approximately 10% vs. approximately 4%)."xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.org/dc/terms/identifier | "doi:10.1086/378071"xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/author | "Tang S."xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/author | "Tang J."xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/author | "Kaslow R.A."xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/author | "Goedert J.J."xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/author | "Coutinho R.A."xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/author | "Detels R."xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/author | "Dorak M.T."xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/author | "Penman-Aguilar A."xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/name | "J Infect Dis"xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/pages | "856-863"xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/title | "Influence of human leukocyte antigen-B22 alleles on the course of human immunodeficiency virus type 1 infection in 3 cohorts of white men."xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://purl.uniprot.org/core/volume | "188"xsd:string |
| http://purl.uniprot.org/citations/12964117 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12964117 |
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| http://purl.uniprot.org/uniprot/#_A0A0E3DCA1-mappedCitation-12964117 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12964117 |
| http://purl.uniprot.org/uniprot/#_A0A068B107-mappedCitation-12964117 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12964117 |
| http://purl.uniprot.org/uniprot/#_A0A068B112-mappedCitation-12964117 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12964117 |
| http://purl.uniprot.org/uniprot/#_A0A068B116-mappedCitation-12964117 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12964117 |