| http://purl.uniprot.org/citations/1319061 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1319061 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1319061 | http://www.w3.org/2000/01/rdf-schema#comment | "The murine Mls-1 antigen is the prototype of endogenous superantigens, molecules whose activities lead to deletion of T cells expressing certain T-cell receptor V beta genes from the mature repertoire. However, Mls-1 also stimulates T cells expressing these particular V beta genes (V beta 6, V beta 7, V beta 8.1, and V beta 9) in vitro, making it one of the strongest known T-cell activators. We have recently reported that the Mls-1 gene is closely linked to the endogenous mammary tumor virus Mtv-7. We now demonstrate that Mls-1 is encoded by the open reading frame in the U3 region of the long terminal repeat of Mtv-7. However, control of expression of this molecule seems complex, depending on the promoter used for the transfection experiments. The sequence of the Mtv-7 open reading frame differs from all other known mammary tumor virus open reading frame sequences in the 3' end, suggesting that the T-cell receptor V beta specificity is conferred by the C terminus of the molecule. The predicted structure of the protein encoded by the open reading frame is consistent with a type II transmembrane molecule where the C terminus is extracellular."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.89.12.5432"xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.89.12.5432"xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/author | "Coffin J.M."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/author | "Coffin J.M."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/author | "Frankel W.N."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/author | "Frankel W.N."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/author | "Huber B.T."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/author | "Huber B.T."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/author | "Beutner U."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/author | "Beutner U."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/author | "Cote M.S."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/author | "Cote M.S."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/pages | "5432-5436"xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/pages | "5432-5436"xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/title | "Mls-1 is encoded by the long terminal repeat open reading frame of the mouse mammary tumor provirus Mtv-7."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/title | "Mls-1 is encoded by the long terminal repeat open reading frame of the mouse mammary tumor provirus Mtv-7."xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/volume | "89"xsd:string |
| http://purl.uniprot.org/citations/1319061 | http://purl.uniprot.org/core/volume | "89"xsd:string |