| http://purl.uniprot.org/citations/1370478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1370478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1370478 | http://www.w3.org/2000/01/rdf-schema#comment | "Genomic clones containing portions of the human cathepsin E (CTSE) gene were isolated from cosmid and lambda recombinant libraries. The regions corresponding to coding, the 5'- and 3'-untranslated, and the exon-intron boundaries of the CTSE gene were identified by sequence and hybridization analysis. The size and placement of the nine exons found in the 17.5-kilobase CTSE gene was highly conserved relative to other aspartic proteinases and provided additional evidence that these proteinases are derived from a common ancestral gene. Segregation and linkage analysis of two informative restriction fragment length polymorphisms (MspI and DraI) indicated that there is a single human CTSE locus located at chromosome 1q31-q32 which is closely linked to the renin gene. Three CTSE transcripts (3.6, 2.6, and 2.1 kilobases) were identified in gastric fundic and antral mucosa poly (A+) RNA, and these appeared identical in size and relative abundance to those contained in poly(A+) RNA from cultured gastric adenocarcinoma cell lines containing CTSE. Sequence analysis of cDNA clones and comparison with the 3'-flanking untranslated region in genomic clones provided evidence that alternative polyadenylation of the primary transcript resulted in the 2.6- and 2.1-kilobase transcripts which constituted greater than 95% of CTSE transcripts found in the stomach."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(18)45989-3"xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(18)45989-3"xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/author | "Azuma T."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/author | "Azuma T."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/author | "Bowcock A.M."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/author | "Bowcock A.M."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/author | "Liu W.G."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/author | "Liu W.G."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/author | "Taggart R.T."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/author | "Taggart R.T."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/author | "Vander Laan D.J."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/author | "Vander Laan D.J."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/pages | "1609-1614"xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/pages | "1609-1614"xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/title | "Human gastric cathepsin E gene. Multiple transcripts result from alternative polyadenylation of the primary transcripts of a single gene locus at 1q31-q32."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/title | "Human gastric cathepsin E gene. Multiple transcripts result from alternative polyadenylation of the primary transcripts of a single gene locus at 1q31-q32."xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/volume | "267"xsd:string |
| http://purl.uniprot.org/citations/1370478 | http://purl.uniprot.org/core/volume | "267"xsd:string |