| http://purl.uniprot.org/citations/1371884 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1371884 | http://www.w3.org/2000/01/rdf-schema#comment | "Interleukin 10 (IL-10), originally identified as a TH2 helper T-cell product able to inhibit cytokine production by TH1 cells, is highly homologous to BCRF1 (viral IL-10), an open reading frame in the Epstein-Barr virus genome. Here, we show that human and viral IL-10 stimulate DNA replication of B lymphocytes activated either via their antigen receptor or via their CD40 antigen. IL-4 and IL-10 display additive effects and induce a strong increase in the number of viable cells. Moreover, IL-10 induces activated B cells to secrete large amounts of IgG, IgA, and IgM, and the combination of IL-10 and IL-4 results in the secretion of the four immunoglobulin isotypes. Thus, IL-10 may play an important role in the amplification of humoral responses."xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.89.5.1890"xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/author | "Garcia E."xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/author | "Moore K.W."xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/author | "Rousset F."xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/author | "Banchereau J."xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/author | "Kastelein R."xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/author | "Peronne C."xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/author | "Defrance T."xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/author | "Hsu D.H."xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/author | "Vezzio N."xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/pages | "1890-1893"xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/title | "Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes."xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://purl.uniprot.org/core/volume | "89"xsd:string |
| http://purl.uniprot.org/citations/1371884 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1371884 |
| http://purl.uniprot.org/citations/1371884 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1371884 |
| http://purl.uniprot.org/uniprot/P22301#attribution-218F5E7C14ABCF012D93F25C5F57139C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1371884 |