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http://purl.uniprot.org/citations/1373520http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1373520http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1373520http://www.w3.org/2000/01/rdf-schema#comment"Interleukin-1 beta (IL-1 beta) mediates a wide range of immune and inflammatory responses. The active cytokine is generated by proteolytic cleavage of an inactive precursor. A complementary DNA encoding a protease that carries out this cleavage has been cloned. Recombinant expression in COS-7 cells enabled the cells to process precursor IL-1 beta to the mature form. Sequence analysis indicated that the enzyme itself may undergo proteolytic processing. The gene encoding the protease was mapped to chromosomal band 11q23, a site frequently involved in rearrangement in human cancers."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.org/dc/terms/identifier"doi:10.1126/science.1373520"xsd:string
http://purl.uniprot.org/citations/1373520http://purl.org/dc/terms/identifier"doi:10.1126/science.1373520"xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Nelson N."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Nelson N."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Druck T."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Druck T."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Huebner K."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Huebner K."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Black R.A."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Black R.A."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Cerretti D.P."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Cerretti D.P."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Kozlosky C.J."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Kozlosky C.J."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"March C.J."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"March C.J."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Greenstreet T.A."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Greenstreet T.A."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Kronheim S.R."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Kronheim S.R."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Cannizzaro L.A."xsd:string
http://purl.uniprot.org/citations/1373520http://purl.uniprot.org/core/author"Cannizzaro L.A."xsd:string