| http://purl.uniprot.org/citations/1373613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1373613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1373613 | http://www.w3.org/2000/01/rdf-schema#comment | "We studied the effect of thyroid status on thyrotropin-releasing hormone receptor (TRH-R) mRNA levels both in vivo and in vitro (GH3 cells) using a cloned rat TRH-R cDNA by RT-PCR. Experimental hypothyroid rats were produced by total thyroidectomy and were then killed 7 days after the operation. TRH receptor binding in the anterior pituitary and serum TSH level were elevated approximately 2-fold and 8-fold, respectively, in 7 day thyroidectomized rats. TRH-R mRNA levels in hypothyroid rats were also increased significantly compared with those of normal rats. In GH3 cells, however, no significant change of TRH-R mRNA level was observed between cultures treated with triiodothyronine (T3, 10(-9) and 10(-7) M) and the untreated group. The present data indicate that 1) the in vivo effects of thyroid status on TRH-R mRNA levels differ from the in vitro one, and that 2) the down regulation of TRH-R binding by thyroid hormone in GH3 cells may be mediated by translational or post-translational mechanisms."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.org/dc/terms/identifier | "doi:10.1016/0006-291x(92)91202-2"xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.org/dc/terms/identifier | "doi:10.1016/0006-291x(92)91202-2"xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Murakami M."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Murakami M."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Mori M."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Mori M."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Yamada M."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Yamada M."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Satoh T."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Satoh T."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Iizuka M."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Iizuka M."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Monden T."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Monden T."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Iriuchijima T."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/author | "Iriuchijima T."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/pages | "367-372"xsd:string |
| http://purl.uniprot.org/citations/1373613 | http://purl.uniprot.org/core/pages | "367-372"xsd:string |