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http://purl.uniprot.org/citations/1375514http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1375514http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1375514http://www.w3.org/2000/01/rdf-schema#comment"A cDNA clone encoding a putative glyceraldehyde 3-phosphate dehydrogenase (GAPD-S) protein specific to spermatogenic cells was isolated from a mouse spermatogenic cell expression library. The Gapd-s cDNA contained 1451 bp of transcribed sequence, including an ATG initiation codon and a poly(A) addition signal. The location of the Gapd-s initiation codon differed from that of other Gapd sequences, resulting in a germ cell GAPD-S protein predicted to contain 105 additional residues at the amino terminus. While GAPD is constitutively expressed in somatic tissues, Northern blot analysis demonstrated that a Gapd-s probe hybridized to a 1.5-kb transcript present only in the testis. The Gapd-s mRNA was first detected during postnatal development in the testes of 20-day-old mice, suggesting that gene expression begins shortly after the appearance of haploid round spermatids. Northern analysis of RNA from isolated mouse pachytene spermatocytes and spermatids confirmed that Gapd-s expression is confined to post-meiotic germ cells. GAPD has been previously proposed to be the key enzyme regulating glycolysis in isolated round spermatids. We hypothesize that the GAPD-S enzyme plays an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.org/dc/terms/identifier"doi:10.1095/biolreprod46.5.869"xsd:string
http://purl.uniprot.org/citations/1375514http://purl.org/dc/terms/identifier"doi:10.1095/biolreprod46.5.869"xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/author"O'Brien D.A."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/author"O'Brien D.A."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/author"Welch J.E."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/author"Welch J.E."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/author"Eddy E.M."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/author"Eddy E.M."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/author"Schatte E.C."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/author"Schatte E.C."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/name"Biol. Reprod."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/name"Biol. Reprod."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/pages"869-878"xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/pages"869-878"xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/title"Expression of a glyceraldehyde 3-phosphate dehydrogenase gene specific to mouse spermatogenic cells."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/title"Expression of a glyceraldehyde 3-phosphate dehydrogenase gene specific to mouse spermatogenic cells."xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/volume"46"xsd:string
http://purl.uniprot.org/citations/1375514http://purl.uniprot.org/core/volume"46"xsd:string
http://purl.uniprot.org/citations/1375514http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1375514
http://purl.uniprot.org/citations/1375514http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1375514