| http://purl.uniprot.org/citations/1376638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1376638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1376638 | http://www.w3.org/2000/01/rdf-schema#comment | "The adhesive interaction between circulating lymphocytes and the high endothelial venules (HEV) of lymph nodes (LN) is mediated by lymphocyte L-selectin, a member of the selectin family of cell adhesion proteins. Previous work has identified a sulfated 50 kd glycoprotein (Sgp50) as an HEV ligand for L-selectin. We now report the purification of this glycoprotein and the utilization of the derived N-terminal amino acid sequence to clone a cDNA. The predicted sequence reveals a novel, mucin-like molecule containing two serine/threonine-rich domains. The mRNA encoding this glycoprotein is preferentially expressed in LN. Antibodies against predicted peptides immunoprecipitate Sgp50 and stain the apical surface of LN HEV. These results thus define a tissue-specific mucin-like endothelial glycoprotein that appears to function as a scaffold that presents carbohydrates to the L-selectin lectin domain."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(92)90612-g"xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(92)90612-g"xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Imai Y."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Imai Y."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Lasky L.A."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Lasky L.A."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Henzel W.J."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Henzel W.J."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Dowbenko D."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Dowbenko D."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Grimley C."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Grimley C."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Singer M.S."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Singer M.S."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Rosen S.D."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Rosen S.D."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Gillett N."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Gillett N."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Watson S.R."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Watson S.R."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Fennie C."xsd:string |
| http://purl.uniprot.org/citations/1376638 | http://purl.uniprot.org/core/author | "Fennie C."xsd:string |