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http://purl.uniprot.org/citations/1379790http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1379790http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1379790http://www.w3.org/2000/01/rdf-schema#comment"Restriction fragments isolated from a 17-kb rat genomic DNA clone containing the gene for apolipoprotein (apo) E were radiolabeled and used to screen a rat liver cDNA library. A cDNA clone hybridizing to a 6-kb genomic DNA fragment was isolated and the nucleotide sequence of the cDNA insert determined. The sequence was homologous to the sequence for human apo C-I and was used to derive the corresponding amino acid sequence. Unlike human apo C-I, mature rat apo C-I contains histidine, lacks valine, and has alanine at the C terminus and aspartate as the N terminus. Screening the rat liver cDNA library with a radiolabeled 1.9-kb restriction fragment from the genomic DNA clone containing the rat apo E gene identified another cDNA clone (ECL cDNA). Nucleotide sequencing yielded a derived 75-amino-acid sequence for the ECL protein with a hydrophobicity profile similar to that of rat apo C-I. Northern analysis demonstrated a 0.50-kb band for ECL mRNA. The tissue-specific expression of the gene is similar to that of rat apo C-I. This study indicates that the rat apo C-I and ECL genes are closely linked, about 4.5 and 12 kb downstream of the apo E gene, respectively."xsd:string
http://purl.uniprot.org/citations/1379790http://purl.org/dc/terms/identifier"doi:10.1016/0003-9861(92)90683-n"xsd:string
http://purl.uniprot.org/citations/1379790http://purl.org/dc/terms/identifier"doi:10.1016/0003-9861(92)90683-n"xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/author"Shen P."xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/author"Shen P."xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/author"Howlett G.J."xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/author"Howlett G.J."xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/name"Arch. Biochem. Biophys."xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/name"Arch. Biochem. Biophys."xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/pages"345-353"xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/pages"345-353"xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/title"Two coding regions closely linked to the rat apolipoprotein E gene: nucleotide sequences of rat apolipoprotein C-I and ECL cDNA."xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/title"Two coding regions closely linked to the rat apolipoprotein E gene: nucleotide sequences of rat apolipoprotein C-I and ECL cDNA."xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/volume"297"xsd:string
http://purl.uniprot.org/citations/1379790http://purl.uniprot.org/core/volume"297"xsd:string
http://purl.uniprot.org/citations/1379790http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1379790
http://purl.uniprot.org/citations/1379790http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1379790
http://purl.uniprot.org/citations/1379790http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1379790
http://purl.uniprot.org/citations/1379790http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1379790
http://purl.uniprot.org/uniprot/P55797http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/1379790
http://purl.uniprot.org/uniprot/P55797#attribution-EBA1D095E077F4ACB300B618C83F89A1http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1379790