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http://purl.uniprot.org/citations/1386336http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1386336http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1386336http://www.w3.org/2000/01/rdf-schema#comment"A human D-type cyclin gene (CCND1/cyclin D1/PRAD1) was previously isolated by virtue of its ability to complement a triple G1 cyclin (Cln) deficiency of Saccharomyces cerevisiae and was also identified as a candidate BCL1 oncogene. We now report the molecular cloning of two additional human D-type cyclin genes, CCND2 (cyclin D2) and CCND3 (cyclin D3). All three human D-type cyclin genes encode small (33-34 kDa) proteins that share an average of 57% identity over the entire coding region and 78% in the cyclin box. The D-type cyclins are most closely related to cyclin A (39% identity) and cyclin E (36%), followed by cyclin B (29%) and cyclin C (21%). Isolation and characterization of genomic clones revealed two pseudogenes corresponding to CCND2 and CCND3, respectively. All three cyclin D genes are interrupted by an intron at the same position. CCND2 has been mapped to chromosome 12p13, and CCND3 has been mapped to chromosome 6p21."xsd:string
http://purl.uniprot.org/citations/1386336http://purl.org/dc/terms/identifier"doi:10.1016/0888-7543(92)90127-e"xsd:string
http://purl.uniprot.org/citations/1386336http://purl.org/dc/terms/identifier"doi:10.1016/0888-7543(92)90127-e"xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/author"Beach D."xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/author"Beach D."xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/author"Xiong Y."xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/author"Xiong Y."xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/author"Ward D.C."xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/author"Ward D.C."xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/author"Menninger J."xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/author"Menninger J."xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/name"Genomics"xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/name"Genomics"xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/pages"575-584"xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/pages"575-584"xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/title"Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins."xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/title"Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins."xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/volume"13"xsd:string
http://purl.uniprot.org/citations/1386336http://purl.uniprot.org/core/volume"13"xsd:string
http://purl.uniprot.org/citations/1386336http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1386336
http://purl.uniprot.org/citations/1386336http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1386336