| http://purl.uniprot.org/citations/13890280 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/13890280 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/13890280 | http://www.w3.org/2000/01/rdf-schema#comment | "Englesberg, E. (University of Pittsburgh, Pittsburgh, Pa.), R L. Anderson, R. Weinberg, N. Lee, P. Hoffee, G. Huttenhauer, and H. Boyer. l-Arabinose-sensitive, l-ribulose 5-phosphate 4-epimerase-deficient mutants of Escherichia coli. J. Bacteriol. 84:137-146. 1962-l-Arabinose-negative mutants of Escherichia coli B/r, ara-53 and ara-139, are deficient in the enzyme l-ribulose 5-phosphate 4-epimerase; ara-53, further analyzed, accumulates large quantities of l-ribulose 5-phosphate when incubated with l-arabinose. The mutant sites are closely linked to the left of the previously ordered l-arabinose mutant sites, and probably represent the structural gene for l-ribulose 5-phosphate 4-epimerase (gene D) in the l-arabinose operon. The inducible levels of l-arabinose isomerase and l-ribulose 5-phosphate 4-epimerase vary correspondingly as a result of mutation in the structural gene for l-ribulokinase (gene B), further substantiating the dual structural and regulatory function of this gene locus. Ara-53 and ara-139 are strongly inhibited by l-arabinose and give rise to l-arabinose-resistant mutants. The one resistant mutant analyzed still lacks the 4-epimerase but is deficient in l-ribulokinase and has increased l-arabinose isomerase activity, a characteristic of a type of mutation in the B gene. It is proposed that accumulation of l-ribulose 5-phosphate is responsible for the inhibition, and that mutation to resistance will involve mutation in the A, B, C, permease, or repressor genes, thus providing a direct method for isolating these types of l-arabinose-negative mutants. Glucose prevents and cures the l-arabinose inhibition."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.84.1.137-146.1962"xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.84.1.137-146.1962"xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Lee N."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Lee N."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Boyer H."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Boyer H."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Anderson R.L."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Anderson R.L."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Englesberg E."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Englesberg E."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Hoffee P."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Hoffee P."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Huttenhauer G."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Huttenhauer G."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Weinberg R."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/author | "Weinberg R."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/date | "1962"xsd:gYear |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/date | "1962"xsd:gYear |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/name | "J. Bacteriol."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/name | "J. Bacteriol."xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/pages | "137-146"xsd:string |
| http://purl.uniprot.org/citations/13890280 | http://purl.uniprot.org/core/pages | "137-146"xsd:string |