http://purl.uniprot.org/citations/1409593 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1409593 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1409593 | http://www.w3.org/2000/01/rdf-schema#comment | "We have isolated a cDNA encoding a transcription factor that binds to the enhancer of major histocompatibility complex (MHC) class I genes. MHC-binding protein 2 (MBP-2) is a 275-kDa protein, containing two sets of widely separated zinc fingers and a stretch of highly acidic amino acids, a putative transactivation domain. The two zinc finger regions, when expressed individually as bacterial fusion proteins, bind with highest affinity to the MHC class I gene enhancer. Several proteins found in mammalian nuclear extracts bind the MHC class I enhancer in an electrophoresis mobility shift assay. Only one of these, a ubiquitously expressed factor, forming a slow-migrating retarded complex, can be supershifted by a MBP-2 antiserum. The same antiserum also precipitates a protein of greater than 250 kDa from COS cells transfected with a MBP-2 expression vector. Our data indicate that MBP-2 is a transcription factor involved in the regulation of MHC class I gene expression."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.89.19.8971"xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.89.19.8971"xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/author | "Bernards R."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/author | "Bernards R."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/author | "Isselbacher K.J."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/author | "Isselbacher K.J."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/author | "Lutz P."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/author | "Lutz P."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/author | "Van't Veer L.J."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/author | "Van't Veer L.J."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/pages | "8971-8975"xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/pages | "8971-8975"xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/title | "Structure and expression of MBP-2: a 275 kDa zinc finger protein that binds to an enhancer of major histocompatibility complex class 1 genes."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/title | "Structure and expression of MBP-2: a 275 kDa zinc finger protein that binds to an enhancer of major histocompatibility complex class 1 genes."xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/volume | "89"xsd:string |
http://purl.uniprot.org/citations/1409593 | http://purl.uniprot.org/core/volume | "89"xsd:string |
http://purl.uniprot.org/citations/1409593 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1409593 |
http://purl.uniprot.org/citations/1409593 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1409593 |