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http://purl.uniprot.org/citations/1417831http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1417831http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1417831http://www.w3.org/2000/01/rdf-schema#comment"Vascular endothelial cell growth factor (VEGF), also known as vascular permeability factor, is an endothelial cell mitogen which stimulates angiogenesis. Here we report that a previously identified receptor tyrosine kinase gene, KDR, encodes a receptor for VEGF. Expression of KDR in CMT-3 (cells which do not contain receptors for VEGF) allows for saturable 125I-VEGF binding with high affinity (KD = 75 pM). Affinity cross-linking of 125I-VEGF to KDR-transfected CMT-3 cells results in specific labeling of two proteins of M(r) = 195 and 235 kDa. The KDR receptor tyrosine kinase shares structural similarities with a recently reported receptor for VEGF, flt, in a manner reminiscent of the similarities between the alpha and beta forms of the PDGF receptors."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.org/dc/terms/identifier"doi:10.1016/0006-291x(92)90483-2"xsd:string
http://purl.uniprot.org/citations/1417831http://purl.org/dc/terms/identifier"doi:10.1016/0006-291x(92)90483-2"xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Boehlen P."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Boehlen P."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Terman B.I."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Terman B.I."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Gospodarowicz D."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Gospodarowicz D."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Armellino D.C."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Armellino D.C."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Carrion M.E."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Carrion M.E."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Dimitrov D."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Dimitrov D."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Dougher-Vermazen M."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/author"Dougher-Vermazen M."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/pages"1579-1586"xsd:string
http://purl.uniprot.org/citations/1417831http://purl.uniprot.org/core/pages"1579-1586"xsd:string