http://purl.uniprot.org/citations/1437147 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1437147 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1437147 | http://www.w3.org/2000/01/rdf-schema#comment | "We have isolated two murine cDNAs designated PCTAIRE-1 and -3 which encode putative serine/threonine-specific protein kinases. The predicted products of PCTAIRE-1 and -3 are 65% homologous and are organized into a core 295-residue kinase domain flanked by unique 161 and 117 amino acid N-terminal and 40 and 39 amino acid C-terminal domains respectively. The kinase domains are approximately 50-55% homologous to members of the cdc2/CDC28 kinase gene family, and each contains a cysteine-for-serine substitution within the conserved PSTAIRE motif. PCTAIRE-1 was ubiquitously expressed as a predominant 3.0-kb transcript and a minor 2.2-kb mRNA resulting from differential polyadenylation. In contrast, PCTAIRE-3 exhibited a more restricted pattern of expression with a single 3.0-kb mRNA detected in brain, kidney and intestine. The PCTAIRE-1 and -3 products produced by in vitro transcription-translation failed to bind to p13suc1 but were precipitated by antibodies directed to Schizosaccharomyces pombe p34cdc2 or to the human PSTAIRE motif. Thus, PCTAIRE-1 and -3 are members of a novel subfamily of cdc2/CDC28-related protein kinases."xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/author | "Okuda T."xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/author | "Okuda T."xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/author | "Downing J.R."xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/author | "Downing J.R."xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/author | "Cleveland J.L."xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/author | "Cleveland J.L."xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/pages | "2249-2258"xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/pages | "2249-2258"xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/title | "PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family."xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/title | "PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family."xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/volume | "7"xsd:string |
http://purl.uniprot.org/citations/1437147 | http://purl.uniprot.org/core/volume | "7"xsd:string |
http://purl.uniprot.org/citations/1437147 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1437147 |
http://purl.uniprot.org/citations/1437147 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1437147 |
http://purl.uniprot.org/citations/1437147 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1437147 |
http://purl.uniprot.org/citations/1437147 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1437147 |
http://purl.uniprot.org/uniprot/Q04899 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1437147 |
http://purl.uniprot.org/uniprot/Q04735 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1437147 |