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http://purl.uniprot.org/citations/1439790http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1439790http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1439790http://www.w3.org/2000/01/rdf-schema#comment"In a screen for transcriptional regulators that control differentiation into the T cell lineage, a complementary DNA was isolated encoding a zinc finger protein (Ikaros) related to the Drosophila gap protein Hunchback. The Ikaros protein binds to and activates the enhancer of a gene encoding an early T cell differentiation antigen, CD3 delta. During development, Ikaros messenger RNA was first detected in the mouse fetal liver and the embryonic thymus when hematopoietic and lymphoid progenitors initially colonize these organs; no expression was observed in the spleen or the bone marrow. The pattern of Ikaros gene expression and its ability to stimulate CD3 delta transcription support the model that Ikaros functions in the specification and maturation of the T lymphocyte."xsd:string
http://purl.uniprot.org/citations/1439790http://purl.org/dc/terms/identifier"doi:10.1126/science.1439790"xsd:string
http://purl.uniprot.org/citations/1439790http://purl.org/dc/terms/identifier"doi:10.1126/science.1439790"xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/author"Derfler B."xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/author"Derfler B."xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/author"Georgopoulos K."xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/author"Georgopoulos K."xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/author"Moore D.D."xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/author"Moore D.D."xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/pages"808-812"xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/pages"808-812"xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/title"Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment."xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/title"Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment."xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/volume"258"xsd:string
http://purl.uniprot.org/citations/1439790http://purl.uniprot.org/core/volume"258"xsd:string
http://purl.uniprot.org/citations/1439790http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1439790
http://purl.uniprot.org/citations/1439790http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1439790
http://purl.uniprot.org/citations/1439790http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1439790
http://purl.uniprot.org/citations/1439790http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1439790