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http://purl.uniprot.org/citations/14499482http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14499482http://www.w3.org/2000/01/rdf-schema#comment"Previous study has demonstrated that the lack of mu-opioid receptor decreased LTP in the dentate gyrus of the hippocampus, suggesting the possibility that the lack of mu-opioid receptor may accompany a change in learning and memory. However, no behavioral study has been undertaken to correlate LTP deficits with spatial memory impairment in mu-opioid receptor knockout mice. Therefore, the present study investigated the hypothesis that mu-opioid receptors contribute to learning and memory by using the Morris water maze, and comparing responses in wild type and mu-opioid receptor gene knockout mice. Our results indicated that mu-opioid receptor knockout mice showed a significant spatial memory impairment compared to wild type in the Morris water maze. This result suggests that the expression of mu-opioid receptor plays an important role in spatial learning and memory examined by Morris water maze."xsd:string
http://purl.uniprot.org/citations/14499482http://purl.org/dc/terms/identifier"doi:10.1016/s0169-328x(03)00291-2"xsd:string
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/author"Lee S.Y."xsd:string
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/author"Yoo J.H."xsd:string
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/author"Loh H.H."xsd:string
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/author"Yan J.J."xsd:string
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/author"Jang C.G."xsd:string
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/author"Ho I.K."xsd:string
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/author"Song D.K."xsd:string
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/name"Brain Res Mol Brain Res"xsd:string
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/pages"68-72"xsd:string
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/title"Impaired water maze learning performance in mu-opioid receptor knockout mice."xsd:string
http://purl.uniprot.org/citations/14499482http://purl.uniprot.org/core/volume"117"xsd:string
http://purl.uniprot.org/citations/14499482http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/14499482
http://purl.uniprot.org/citations/14499482http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/14499482
http://purl.uniprot.org/uniprot/#_A0A0R4J0Z2-mappedCitation-14499482http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14499482
http://purl.uniprot.org/uniprot/#_E9Q7D3-mappedCitation-14499482http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14499482
http://purl.uniprot.org/uniprot/#_E9Q7D4-mappedCitation-14499482http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14499482
http://purl.uniprot.org/uniprot/#_A1KZZ4-mappedCitation-14499482http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14499482
http://purl.uniprot.org/uniprot/#_A1KZZ6-mappedCitation-14499482http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14499482
http://purl.uniprot.org/uniprot/#_A1KZZ7-mappedCitation-14499482http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14499482
http://purl.uniprot.org/uniprot/#_A1XGX2-mappedCitation-14499482http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14499482
http://purl.uniprot.org/uniprot/#_A4GE58-mappedCitation-14499482http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14499482