| http://purl.uniprot.org/citations/14527420 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14527420 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14527420 | http://www.w3.org/2000/01/rdf-schema#comment | "The double Holliday junction (dHJ) is generally regarded to be a key intermediate of meiotic recombination, whose resolution is critical for the formation of crossover recombinants. In fission yeast, the Mus81-Eme1 endonuclease has been implicated in resolving dHJs. Consistent with this role, we show that Mus81-Eme1 is required for generating meiotic crossovers. However, purified Mus81-Eme1 prefers to cleave junctions that mimic those formed during the transition from double-strand break to dHJ. Crucially, these junctions are cleaved by Mus81-Eme1 in precisely the right orientation to guarantee the formation of a crossover every time. These data demonstrate how crossovers could arise without forming or resolving dHJs using an enzyme that is widely conserved amongst eukaryotes."xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(03)00343-5"xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(03)00343-5"xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/author | "Dixon J."xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/author | "Dixon J."xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/author | "Osman F."xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/author | "Osman F."xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/author | "Doe C.L."xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/author | "Doe C.L."xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/author | "Whitby M.C."xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/author | "Whitby M.C."xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/pages | "761-774"xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/pages | "761-774"xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/title | "Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis."xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/title | "Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis."xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/14527420 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14527420 |
| http://purl.uniprot.org/citations/14527420 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14527420 |