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http://purl.uniprot.org/citations/14532006http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14532006http://www.w3.org/2000/01/rdf-schema#comment"The mitochondrial ribosome is responsible for the biosynthesis of protein components crucial to the generation of ATP in the eukaryotic cell. Because the protein:RNA ratio in the mitochondrial ribosome (approximately 69:approximately 31) is the inverse of that of its prokaryotic counterpart (approximately 33:approximately 67), it was thought that the additional and/or larger proteins of the mitochondrial ribosome must compensate for the shortened rRNAs. Here, we present a three-dimensional cryo-electron microscopic map of the mammalian mitochondrial 55S ribosome carrying a tRNA at its P site, and we find that instead, many of the proteins occupy new positions in the ribosome. Furthermore, unlike cytoplasmic ribosomes, the mitochondrial ribosome possesses intersubunit bridges composed largely of proteins; it has a gatelike structure at its mRNA entrance, perhaps involved in recruiting unique mitochondrial mRNAs; and it has a polypeptide exit tunnel that allows access to the solvent before the exit site, suggesting a unique nascent-polypeptide exit mechanism."xsd:string
http://purl.uniprot.org/citations/14532006http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(03)00762-1"xsd:string
http://purl.uniprot.org/citations/14532006http://purl.uniprot.org/core/author"Spremulli L.L."xsd:string
http://purl.uniprot.org/citations/14532006http://purl.uniprot.org/core/author"Koc E.C."xsd:string
http://purl.uniprot.org/citations/14532006http://purl.uniprot.org/core/author"Datta P.P."xsd:string
http://purl.uniprot.org/citations/14532006http://purl.uniprot.org/core/author"Agrawal R.K."xsd:string
http://purl.uniprot.org/citations/14532006http://purl.uniprot.org/core/author"Booth T.M."xsd:string
http://purl.uniprot.org/citations/14532006http://purl.uniprot.org/core/author"Sharma M.R."xsd:string
http://purl.uniprot.org/citations/14532006http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14532006http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/14532006http://purl.uniprot.org/core/pages"97-108"xsd:string
http://purl.uniprot.org/citations/14532006http://purl.uniprot.org/core/title"Structure of the mammalian mitochondrial ribosome reveals an expanded functional role for its component proteins."xsd:string
http://purl.uniprot.org/citations/14532006http://purl.uniprot.org/core/volume"115"xsd:string
http://purl.uniprot.org/citations/14532006http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/14532006
http://purl.uniprot.org/citations/14532006http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/14532006
http://purl.uniprot.org/uniprot/#_P52815-mappedCitation-14532006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14532006
http://purl.uniprot.org/uniprot/#_Q14197-mappedCitation-14532006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14532006
http://purl.uniprot.org/uniprot/#_Q15070-mappedCitation-14532006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14532006
http://purl.uniprot.org/uniprot/#_O15235-mappedCitation-14532006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14532006
http://purl.uniprot.org/uniprot/#_P09001-mappedCitation-14532006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14532006
http://purl.uniprot.org/uniprot/#_Q7Z7F7-mappedCitation-14532006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14532006
http://purl.uniprot.org/uniprot/#_Q7Z7H8-mappedCitation-14532006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14532006
http://purl.uniprot.org/uniprot/#_Q13084-mappedCitation-14532006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14532006
http://purl.uniprot.org/uniprot/#_Q4U2R6-mappedCitation-14532006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14532006