http://purl.uniprot.org/citations/14532006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14532006 | http://www.w3.org/2000/01/rdf-schema#comment | "The mitochondrial ribosome is responsible for the biosynthesis of protein components crucial to the generation of ATP in the eukaryotic cell. Because the protein:RNA ratio in the mitochondrial ribosome (approximately 69:approximately 31) is the inverse of that of its prokaryotic counterpart (approximately 33:approximately 67), it was thought that the additional and/or larger proteins of the mitochondrial ribosome must compensate for the shortened rRNAs. Here, we present a three-dimensional cryo-electron microscopic map of the mammalian mitochondrial 55S ribosome carrying a tRNA at its P site, and we find that instead, many of the proteins occupy new positions in the ribosome. Furthermore, unlike cytoplasmic ribosomes, the mitochondrial ribosome possesses intersubunit bridges composed largely of proteins; it has a gatelike structure at its mRNA entrance, perhaps involved in recruiting unique mitochondrial mRNAs; and it has a polypeptide exit tunnel that allows access to the solvent before the exit site, suggesting a unique nascent-polypeptide exit mechanism."xsd:string |
http://purl.uniprot.org/citations/14532006 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(03)00762-1"xsd:string |
http://purl.uniprot.org/citations/14532006 | http://purl.uniprot.org/core/author | "Spremulli L.L."xsd:string |
http://purl.uniprot.org/citations/14532006 | http://purl.uniprot.org/core/author | "Koc E.C."xsd:string |
http://purl.uniprot.org/citations/14532006 | http://purl.uniprot.org/core/author | "Datta P.P."xsd:string |
http://purl.uniprot.org/citations/14532006 | http://purl.uniprot.org/core/author | "Agrawal R.K."xsd:string |
http://purl.uniprot.org/citations/14532006 | http://purl.uniprot.org/core/author | "Booth T.M."xsd:string |
http://purl.uniprot.org/citations/14532006 | http://purl.uniprot.org/core/author | "Sharma M.R."xsd:string |
http://purl.uniprot.org/citations/14532006 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/14532006 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/14532006 | http://purl.uniprot.org/core/pages | "97-108"xsd:string |
http://purl.uniprot.org/citations/14532006 | http://purl.uniprot.org/core/title | "Structure of the mammalian mitochondrial ribosome reveals an expanded functional role for its component proteins."xsd:string |
http://purl.uniprot.org/citations/14532006 | http://purl.uniprot.org/core/volume | "115"xsd:string |
http://purl.uniprot.org/citations/14532006 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14532006 |
http://purl.uniprot.org/citations/14532006 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14532006 |
http://purl.uniprot.org/uniprot/#_P52815-mappedCitation-14532006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14532006 |
http://purl.uniprot.org/uniprot/#_Q14197-mappedCitation-14532006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14532006 |
http://purl.uniprot.org/uniprot/#_Q15070-mappedCitation-14532006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14532006 |
http://purl.uniprot.org/uniprot/#_O15235-mappedCitation-14532006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14532006 |
http://purl.uniprot.org/uniprot/#_P09001-mappedCitation-14532006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14532006 |
http://purl.uniprot.org/uniprot/#_Q7Z7F7-mappedCitation-14532006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14532006 |
http://purl.uniprot.org/uniprot/#_Q7Z7H8-mappedCitation-14532006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14532006 |
http://purl.uniprot.org/uniprot/#_Q13084-mappedCitation-14532006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14532006 |
http://purl.uniprot.org/uniprot/#_Q4U2R6-mappedCitation-14532006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14532006 |