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http://purl.uniprot.org/citations/14535885http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14535885http://www.w3.org/2000/01/rdf-schema#comment"Blue light inhibits elongation of etiolated Arabidopsis thaliana hypocotyls during the first 30 min of irradiation by a mechanism that depends on the phototropin 1 (phot1) photoreceptor. The cryptochrome 1 (cry1) photoreceptor begins to exert control after 30 min. To identify genes responsible for the cry1 phase of growth inhibition, mRNA expression profiles of cry1 and wild-type seedlings were compared using DNA microarrays. Of the roughly 420 genes found to be differentially expressed at the point of cry1 response incipience, approximately half were expressed higher and half lower in cry1 relative to the wild type. Many of the cry1-dependent genes encoded kinases, transcription factors, cell cycle regulators, cell wall metabolism enzymes, gibberellic acid (GA) biosynthesis enzymes, and auxin response factors. High-resolution growth studies supported the hypothesis that genes in the last two categories were indeed relevant to cry1-mediated growth control. Inhibiting GA4 biosynthesis with a 3beta-hydroxylase inhibitor (Ca-prohexadione) restored wild-type response kinetics in cry1 and completely suppressed its long-hypocotyl phenotype in blue light. Co-treatment of cry1 seedlings with Ca-prohexadione plus GA4 completely reversed the effects of the inhibitor, restoring the long-hypocotyl phenotype typical of the mutant. Treatment of wild-type seedlings with GA4 was not sufficient to phenocopy cry1 seedlings, but co-treatment with IAA plus GA4 produced cry1-like growth kinetics for a period of approximately 5 h. The genomic and physiological data together indicate that blue light acting through cry1 quickly affects the expression of many genes, a subset of which suppresses stem growth by repressing GA and auxin levels and/or sensitivity."xsd:string
http://purl.uniprot.org/citations/14535885http://purl.org/dc/terms/identifier"doi:10.1046/j.1365-313x.2003.01870.x"xsd:string
http://purl.uniprot.org/citations/14535885http://purl.uniprot.org/core/author"Spalding E.P."xsd:string
http://purl.uniprot.org/citations/14535885http://purl.uniprot.org/core/author"Folta K.M."xsd:string
http://purl.uniprot.org/citations/14535885http://purl.uniprot.org/core/author"Karlin-Neumann G."xsd:string
http://purl.uniprot.org/citations/14535885http://purl.uniprot.org/core/author"Bottini R."xsd:string
http://purl.uniprot.org/citations/14535885http://purl.uniprot.org/core/author"Pontin M.A."xsd:string
http://purl.uniprot.org/citations/14535885http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14535885http://purl.uniprot.org/core/name"Plant J"xsd:string
http://purl.uniprot.org/citations/14535885http://purl.uniprot.org/core/pages"203-214"xsd:string
http://purl.uniprot.org/citations/14535885http://purl.uniprot.org/core/title"Genomic and physiological studies of early cryptochrome 1 action demonstrate roles for auxin and gibberellin in the control of hypocotyl growth by blue light."xsd:string
http://purl.uniprot.org/citations/14535885http://purl.uniprot.org/core/volume"36"xsd:string
http://purl.uniprot.org/citations/14535885http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/14535885
http://purl.uniprot.org/citations/14535885http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/14535885
http://purl.uniprot.org/uniprot/#_F4KHY3-mappedCitation-14535885http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14535885
http://purl.uniprot.org/uniprot/#_F4KHY4-mappedCitation-14535885http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14535885
http://purl.uniprot.org/uniprot/#_A0A2H1ZEJ2-mappedCitation-14535885http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14535885
http://purl.uniprot.org/uniprot/#_A0A1I9LT94-mappedCitation-14535885http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14535885
http://purl.uniprot.org/uniprot/#_A0A1P8AQS9-mappedCitation-14535885http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14535885
http://purl.uniprot.org/uniprot/#_A0A1P8AXT9-mappedCitation-14535885http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14535885
http://purl.uniprot.org/uniprot/#_A0A1P8AXY5-mappedCitation-14535885http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14535885
http://purl.uniprot.org/uniprot/#_A0A1P8B8H4-mappedCitation-14535885http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14535885
http://purl.uniprot.org/uniprot/#_A0A1P8B8H8-mappedCitation-14535885http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14535885
http://purl.uniprot.org/uniprot/#_A0A1P8B267-mappedCitation-14535885http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14535885