http://purl.uniprot.org/citations/14555717 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14555717 | http://www.w3.org/2000/01/rdf-schema#comment | "In adult mice, long-term potentiation (LTP) of synaptic transmission at CA3-to-CA1 synapses induced by tetanic stimulation requires L-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors containing GluR-A subunits. Here, we report a GluR-A-independent form of LTP, which is comparable in size to LTP in wild-type mice at postnatal day 14 (P14) but diminishes between P14 and P42 in brain slices of GluR-A-deficient mice. The GluR-A-independent form of LTP is sensitive to D(-)-2-amino-5-phosphonopentanoic acid (D-AP5), but lacks short-term potentiation (STP) and can also be observed in the pairing induction protocol. As judged by unaltered paired-pulse facilitation, this LTP form is postsynaptically expressed despite depleted extrasynaptic AMPA receptor pools with reduced levels of GluR-B, which accumulates in somata and synapses of CA1 pyramidal neurons in GluR-A-deficient mice. Our results show that in the developing hippocampus synaptic plasticity can be expressed by AMPA receptors lacking the GluR-A subunit."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.org/dc/terms/identifier | "doi:10.1113/jphysiol.2003.053637"xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Sprengel R."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Seeburg P.H."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Andersen P."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Sakmann B."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Jensen V."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Rozov A."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Borchardt T."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Burnashev N."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Frotscher M."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Hvalby O."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Kaiser K.M."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Adelmann G."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/author | "Brix C."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/name | "J Physiol"xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/pages | "843-856"xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/title | "A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A."xsd:string |
http://purl.uniprot.org/citations/14555717 | http://purl.uniprot.org/core/volume | "553"xsd:string |
http://purl.uniprot.org/citations/14555717 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14555717 |
http://purl.uniprot.org/citations/14555717 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14555717 |
http://purl.uniprot.org/uniprot/P23819#attribution-4C0F28C96076D6BA857D94C5D1C8E42E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/14555717 |
http://purl.uniprot.org/uniprot/P23818#attribution-4C0F28C96076D6BA857D94C5D1C8E42E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/14555717 |