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http://purl.uniprot.org/citations/14555717http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14555717http://www.w3.org/2000/01/rdf-schema#comment"In adult mice, long-term potentiation (LTP) of synaptic transmission at CA3-to-CA1 synapses induced by tetanic stimulation requires L-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors containing GluR-A subunits. Here, we report a GluR-A-independent form of LTP, which is comparable in size to LTP in wild-type mice at postnatal day 14 (P14) but diminishes between P14 and P42 in brain slices of GluR-A-deficient mice. The GluR-A-independent form of LTP is sensitive to D(-)-2-amino-5-phosphonopentanoic acid (D-AP5), but lacks short-term potentiation (STP) and can also be observed in the pairing induction protocol. As judged by unaltered paired-pulse facilitation, this LTP form is postsynaptically expressed despite depleted extrasynaptic AMPA receptor pools with reduced levels of GluR-B, which accumulates in somata and synapses of CA1 pyramidal neurons in GluR-A-deficient mice. Our results show that in the developing hippocampus synaptic plasticity can be expressed by AMPA receptors lacking the GluR-A subunit."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.org/dc/terms/identifier"doi:10.1113/jphysiol.2003.053637"xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Sprengel R."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Seeburg P.H."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Andersen P."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Sakmann B."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Jensen V."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Rozov A."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Borchardt T."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Burnashev N."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Frotscher M."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Hvalby O."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Kaiser K.M."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Adelmann G."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/author"Brix C."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/name"J Physiol"xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/pages"843-856"xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/title"A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A."xsd:string
http://purl.uniprot.org/citations/14555717http://purl.uniprot.org/core/volume"553"xsd:string
http://purl.uniprot.org/citations/14555717http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/14555717
http://purl.uniprot.org/citations/14555717http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/14555717
http://purl.uniprot.org/uniprot/P23819#attribution-4C0F28C96076D6BA857D94C5D1C8E42Ehttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/14555717
http://purl.uniprot.org/uniprot/P23818#attribution-4C0F28C96076D6BA857D94C5D1C8E42Ehttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/14555717