| http://purl.uniprot.org/citations/14556380 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14556380 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14556380 | http://www.w3.org/2000/01/rdf-schema#comment | "A fine regulation of the amiloride-sensitive Epithelial Sodium Channel (ENaC), made of alpha, beta and gamma subunits, is crucial for maintenance of Na+ balance and blood pressure. Both beta- and gamma-ENaC participate in negative regulation by interacting with Nedd4-2, an E3 ubiquitin-ligase. Disruption of this interaction results in increased ENaC activity (Liddle syndrome). By two-hybrid screenings, we identified new potential partners of alpha-ENaC: WWP1 (E3 ubiquitin-ligase protein), UBC9 and TSG101 (E2 ubiquitin/SUMO-conjugating enzymes) and confirmed these interactions in GST pull-down assays. All these partners are implicated in protein trafficking and could be involved in the regulation of ENaC activity."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1631-0691(03)00154-9"xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1631-0691(03)00154-9"xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/author | "Galand C."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/author | "Galand C."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/author | "Nicolas G."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/author | "Nicolas G."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/author | "Lecomte M.-C."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/author | "Lecomte M.-C."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/author | "Dhermy D."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/author | "Dhermy D."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/author | "Malbert-Colas L."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/author | "Malbert-Colas L."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/name | "C. R. Biol."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/name | "C. R. Biol."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/pages | "615-624"xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/pages | "615-624"xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/title | "Identification of new partners of the epithelial sodium channel alpha subunit."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/title | "Identification of new partners of the epithelial sodium channel alpha subunit."xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/volume | "326"xsd:string |
| http://purl.uniprot.org/citations/14556380 | http://purl.uniprot.org/core/volume | "326"xsd:string |