| http://purl.uniprot.org/citations/14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14560002 | http://www.w3.org/2000/01/rdf-schema#comment | "Tumor suppressor p53 controls cell cycle progression and apoptosis following DNA damage, thus minimizing carcinogenesis. Mutations in the human DDB2 gene generate the E subgroup of xeroderma pigmentosum (XP-E). We report here that XP-E strains are defective in UV irradiation-induced apoptosis due to severely reduced basal and UV-induced p53 levels. These defects are restored by infection with a p53 cDNA expression construct or with a DDB2 expression construct if and only if it contains intron 4, which includes a nonmutated p53 consensus-binding site. We propose that both before and after UV irradiation, DDB2 directly regulates p53 levels, while DDB2 expression is itself regulated by p53."xsd:string |
| http://purl.uniprot.org/citations/14560002 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.23.21.7540-7553.2003"xsd:string |
| http://purl.uniprot.org/citations/14560002 | http://purl.uniprot.org/core/author | "Itoh T."xsd:string |
| http://purl.uniprot.org/citations/14560002 | http://purl.uniprot.org/core/author | "Linn S."xsd:string |
| http://purl.uniprot.org/citations/14560002 | http://purl.uniprot.org/core/author | "O'Shea C."xsd:string |
| http://purl.uniprot.org/citations/14560002 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14560002 | http://purl.uniprot.org/core/name | "Mol Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/14560002 | http://purl.uniprot.org/core/pages | "7540-7553"xsd:string |
| http://purl.uniprot.org/citations/14560002 | http://purl.uniprot.org/core/title | "Impaired regulation of tumor suppressor p53 caused by mutations in the xeroderma pigmentosum DDB2 gene: mutual regulatory interactions between p48(DDB2) and p53."xsd:string |
| http://purl.uniprot.org/citations/14560002 | http://purl.uniprot.org/core/volume | "23"xsd:string |
| http://purl.uniprot.org/citations/14560002 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14560002 |
| http://purl.uniprot.org/citations/14560002 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14560002 |
| http://purl.uniprot.org/uniprot/#_A0A087WXZ1-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |
| http://purl.uniprot.org/uniprot/#_A0A087X1Q1-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |
| http://purl.uniprot.org/uniprot/#_A0A0C4KX50-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |
| http://purl.uniprot.org/uniprot/#_A0A218MJE5-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |
| http://purl.uniprot.org/uniprot/#_A0A087WT22-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |
| http://purl.uniprot.org/uniprot/#_A0A0A0U7X4-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |
| http://purl.uniprot.org/uniprot/#_A0A346XLN8-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |
| http://purl.uniprot.org/uniprot/#_A0A346XLS8-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |
| http://purl.uniprot.org/uniprot/#_A0A346XLT4-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |
| http://purl.uniprot.org/uniprot/#_D5KL86-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |
| http://purl.uniprot.org/uniprot/#_E2G6R5-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |
| http://purl.uniprot.org/uniprot/#_Q1HGV3-mappedCitation-14560002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14560002 |