http://purl.uniprot.org/citations/14564011 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14564011 | http://www.w3.org/2000/01/rdf-schema#comment | "The Rac1 guanosine triphosphatase (GTPase) has been implicated in multiple cellular functions, including actin dynamics, proliferation, apoptosis, adhesion, and migration resulting from signaling by multiple receptors, including the B cell antigen receptor (BCR). We used conditional gene targeting to generate mice with specific Rac1 deficiency in the B cell lineage. In the absence of both Rac1 and the highly related Rac2, B cell development was almost completely blocked. Both GTPases were required to transduce BCR signals leading to proliferation, survival and up-regulation of BAFF-R, a receptor for BAFF, a key survival molecule required for B cell development and maintenance."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1089709"xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/author | "Tybulewicz V.L."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/author | "Williams D.A."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/author | "Ooi S.K."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/author | "Ruf S."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/author | "Cancro M.P."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/author | "Smith S.H."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/author | "Mathiot A."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/author | "Vanes L."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/author | "Reynolds L.F."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/author | "Walmsley M.J."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/pages | "459-462"xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/title | "Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling."xsd:string |
http://purl.uniprot.org/citations/14564011 | http://purl.uniprot.org/core/volume | "302"xsd:string |
http://purl.uniprot.org/citations/14564011 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14564011 |
http://purl.uniprot.org/citations/14564011 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14564011 |
http://purl.uniprot.org/uniprot/#_A0A0X1KG58-mappedCitation-14564011 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14564011 |
http://purl.uniprot.org/uniprot/#_A0A2R8VH29-mappedCitation-14564011 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14564011 |
http://purl.uniprot.org/uniprot/#_A0A2R8VHH0-mappedCitation-14564011 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14564011 |
http://purl.uniprot.org/uniprot/#_A0A0U1RQ87-mappedCitation-14564011 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14564011 |
http://purl.uniprot.org/uniprot/#_O88643-mappedCitation-14564011 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14564011 |