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http://purl.uniprot.org/citations/14574404http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14574404http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14574404http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14574404http://www.w3.org/2000/01/rdf-schema#comment"Chromosome 6 is a metacentric chromosome that constitutes about 6% of the human genome. The finished sequence comprises 166,880,988 base pairs, representing the largest chromosome sequenced so far. The entire sequence has been subjected to high-quality manual annotation, resulting in the evidence-supported identification of 1,557 genes and 633 pseudogenes. Here we report that at least 96% of the protein-coding genes have been identified, as assessed by multi-species comparative sequence analysis, and provide evidence for the presence of further, otherwise unsupported exons/genes. Among these are genes directly implicated in cancer, schizophrenia, autoimmunity and many other diseases. Chromosome 6 harbours the largest transfer RNA gene cluster in the genome; we show that this cluster co-localizes with a region of high transcriptional activity. Within the essential immune loci of the major histocompatibility complex, we find HLA-B to be the most polymorphic gene on chromosome 6 and in the human genome."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.org/dc/terms/identifier"doi:10.1038/nature02055"xsd:string
http://purl.uniprot.org/citations/14574404http://purl.org/dc/terms/identifier"doi:10.1038/nature02055"xsd:string
http://purl.uniprot.org/citations/14574404http://purl.org/dc/terms/identifier"doi:10.1038/nature02055"xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ainscough R."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ainscough R."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ainscough R."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Almeida J.P."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Almeida J.P."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Almeida J.P."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ambrose K.D."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ambrose K.D."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ambrose K.D."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Andrews T.D."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Andrews T.D."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Andrews T.D."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ashurst J.L."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ashurst J.L."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ashurst J.L."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ashwell R.I.S."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ashwell R.I.S."xsd:string
http://purl.uniprot.org/citations/14574404http://purl.uniprot.org/core/author"Ashwell R.I.S."xsd:string