| http://purl.uniprot.org/citations/14574415 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14574415 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14574415 | http://www.w3.org/2000/01/rdf-schema#comment | "The events of cell reproduction are governed by oscillations in the activities of cyclin-dependent kinases (Cdks). Cdks control the cell cycle by catalysing the transfer of phosphate from ATP to specific protein substrates. Despite their importance in cell-cycle control, few Cdk substrates have been identified. Here, we screened a budding yeast proteomic library for proteins that are directly phosphorylated by Cdk1 in whole-cell extracts. We identified about 200 Cdk1 substrates, several of which are phosphorylated in vivo in a Cdk1-dependent manner. The identities of these substrates reveal that Cdk1 employs a global regulatory strategy involving phosphorylation of other regulatory molecules as well as phosphorylation of the molecular machines that drive cell-cycle events. Detailed analysis of these substrates is likely to yield important insights into cell-cycle regulation."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.org/dc/terms/identifier | "doi:10.1038/nature02062"xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.org/dc/terms/identifier | "doi:10.1038/nature02062"xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Shokat K.M."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Shokat K.M."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Morgan D.O."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Morgan D.O."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Shah K."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Shah K."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Blethrow J.D."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Blethrow J.D."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Paraz M."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Paraz M."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Quang P.N."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Quang P.N."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Ubersax J.A."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Ubersax J.A."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Woodbury E.L."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/author | "Woodbury E.L."xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/14574415 | http://purl.uniprot.org/core/name | "Nature"xsd:string |