| http://purl.uniprot.org/citations/14579377 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14579377 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14579377 | http://www.w3.org/2000/01/rdf-schema#comment | "We have used whole-mount in situ hybridization to analyze Na,K-ATPase alpha and beta subunit gene expression in the developing zebrafish ear. Four alpha1-like (alpha1a.1, alpha1a.2, alpha1a.4, and alpha1a.5) and two beta (beta1a and beta2b) subunit genes are expressed in ear beginning at mid-somitogenesis. Each gene exhibits a distinct spatial and temporal expression pattern. The alpha1a.1 gene was ubiquitously expressed in the otic epithelium from mid-somitogenesis to 24 hr postfertilization (hpf). Expression of this gene was gradually reduced and by 48 hpf, alpha1a.1 transcripts were no longer detectable in the ear. The alpha1a.2 and alpha1a.5 genes were expressed in regions that correspond to the anterior macula, lateral crista, and semicircular canal projections up to 48 hpf. At later stages, expression of these genes was limited to cells in the dorsolateral septum and semicircular canal projections. alpha1a.4 and beta1a transcripts were ubiquitously expressed during ear development and were present in most otic tissues at 5 days postfertilization (dpf). Expression of the beta2b gene, on the other hand, was restricted to subsets of cells that form sensory epithelia. These results strongly suggest different functional roles for individual Na,K-ATPase genes in zebrafish ear development. Na,K-ATPase genes are likely to represent useful markers for the analysis of zebrafish otogenesis."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.org/dc/terms/identifier | "doi:10.1002/dvdy.10391"xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Levenson R."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Levenson R."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Degrave A."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Degrave A."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Thisse B."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Thisse B."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Thisse C."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Thisse C."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Canfield V."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Canfield V."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Blasiole B."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Blasiole B."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Mohideen M.A."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Mohideen M.A."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Boehmler W."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/author | "Boehmler W."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/name | "Dev. Dyn."xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/name | "Dev Dyn"xsd:string |
| http://purl.uniprot.org/citations/14579377 | http://purl.uniprot.org/core/pages | "386-392"xsd:string |