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http://purl.uniprot.org/citations/14580344http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14580344http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14580344http://www.w3.org/2000/01/rdf-schema#comment"The twin-arginine translocation (Tat) machinery of the Escherichia coli inner membrane is dedicated to the export of proteins harboring a conserved SRRxFLK motif in their signal sequence. TatA, TatB, and TatC are the functionally essential constituents of the Tat machinery, but their precise function is unknown. Using site-specific crosslinking, we have analyzed interactions of the twin-arginine precursor preSufI with the Tat proteins upon targeting to inner membrane vesicles. TatA association is observed only in the presence of a transmembrane H(+) gradient. TatB is found in contact with the entire signal sequence and adjacent parts of mature SufI. Interaction of TatC with preSufI is, however, restricted to a discrete area around the consensus motif. The results reveal a hierarchy in targeting of a Tat substrate such that for the primary interaction, TatC is both necessary and sufficient while a subsequent association with TatB likely mediates transfer from TatC to the actual Tat pore."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.org/dc/terms/identifier"doi:10.1016/s1097-2765(03)00398-8"xsd:string
http://purl.uniprot.org/citations/14580344http://purl.org/dc/terms/identifier"doi:10.1016/s1097-2765(03)00398-8"xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Muller M."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Muller M."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Koch H.G."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Koch H.G."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Brunner J."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Brunner J."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Eisner G."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Eisner G."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Alami M."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Alami M."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Deitermann S."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Deitermann S."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Luke I."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/author"Luke I."xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/name"Mol. Cell"xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/name"Mol. Cell"xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/pages"937-946"xsd:string
http://purl.uniprot.org/citations/14580344http://purl.uniprot.org/core/pages"937-946"xsd:string