| http://purl.uniprot.org/citations/14592933 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14592933 | http://www.w3.org/2000/01/rdf-schema#comment | "A previous survey of mouse inbred strains revealed a wide range in self-selected fat intake, from 26 to 83% of energy. The BALB/cByJ strain selected a lower percentage of fat intake (36%) than all other strains tested except for the CAST/Ei. BALB/cByJ mice are deficient in the short-chain acyl-CoA dehydrogenase (SCAD) enzyme due to a spontaneous mutation in Acads. We hypothesized that this deficiency would alter fat appetite and used three behavioral test paradigms to compare the response of BALB/cByKz. Acads -/- and BALB/cByKz. Acads +/+ mice to fat stimuli. First, during 10-day exposure to a macronutrient self-selection diet, Acads -/-mice consumed proportionately less fat and more carbohydrate than Acads +/+ mice, yet total energy intake was similar between strains. Next, in 48-h two-bottle preference tests, Acads +/+ mice displayed a preference for 50% corn oil, but Acads -/-mice did not. Finally, in brief-access taste tests employing successive 5-s presentations of corn oil in an ascending concentration series ending with 50%, there were no effects of strain on total licks, indicating that Acads does not alter acute orosensory response to this fat stimulus. With 15-s presentations, however, the Acads +/+ mice licked more of the 50% oil than Acads -/-, suggesting orosensory effects related to the increased exposure time. In contrast to corn oil, there were no strain differences in licking response to sucrose solution in either the two-bottle or brief-access taste tests. The observation that SCAD-deficient mice display altered postingestive responses to dietary fat provides further evidence for the metabolic control of feeding."xsd:string |
| http://purl.uniprot.org/citations/14592933 | http://purl.org/dc/terms/identifier | "doi:10.1152/ajpregu.00488.2003"xsd:string |
| http://purl.uniprot.org/citations/14592933 | http://purl.uniprot.org/core/author | "Volaufova J."xsd:string |
| http://purl.uniprot.org/citations/14592933 | http://purl.uniprot.org/core/author | "York B."xsd:string |
| http://purl.uniprot.org/citations/14592933 | http://purl.uniprot.org/core/author | "Smith Richards B.K."xsd:string |
| http://purl.uniprot.org/citations/14592933 | http://purl.uniprot.org/core/author | "Belton B.N."xsd:string |
| http://purl.uniprot.org/citations/14592933 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14592933 | http://purl.uniprot.org/core/name | "Am J Physiol Regul Integr Comp Physiol"xsd:string |
| http://purl.uniprot.org/citations/14592933 | http://purl.uniprot.org/core/pages | "R311-9"xsd:string |
| http://purl.uniprot.org/citations/14592933 | http://purl.uniprot.org/core/title | "Mice bearing Acads mutation display altered postingestive but not 5-s orosensory response to dietary fat."xsd:string |
| http://purl.uniprot.org/citations/14592933 | http://purl.uniprot.org/core/volume | "286"xsd:string |
| http://purl.uniprot.org/citations/14592933 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14592933 |
| http://purl.uniprot.org/citations/14592933 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14592933 |
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| http://purl.uniprot.org/uniprot/#_Q6LCR2-mappedCitation-14592933 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14592933 |
| http://purl.uniprot.org/uniprot/Q07417 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/14592933 |
| http://purl.uniprot.org/uniprot/Q6LCR2 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/14592933 |