RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/14596909http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14596909http://www.w3.org/2000/01/rdf-schema#comment"Insulin receptor substrate p53 (IRSp53) is a key player in cytoskeletal dynamics, interacting with the actin modulators WAVE2 and Mena. Here, we identified a PDZ protein, MALS, as an IRSp53-interacting protein using a yeast two-hybrid screen. A pull-down assay showed that IRSp53 and MALS interact through the PDZ domain of MALS and the C-terminal PDZ-binding sequence of IRSp53. Their interaction in MDCK cells was also demonstrated by co-immunoprecipitation. Immunocytochemistry showed the colocalization of IRSp53 and MALS at cell-cell contacts. Cytochalasin D induced the redistribution of both proteins to the cytosol. Thus, MALS is a partner of IRSp53 anchoring the actin-based membrane cytoskeleton at cell-cell contacts."xsd:string
http://purl.uniprot.org/citations/14596909http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(03)01074-3"xsd:string
http://purl.uniprot.org/citations/14596909http://purl.uniprot.org/core/author"Hori K."xsd:string
http://purl.uniprot.org/citations/14596909http://purl.uniprot.org/core/author"Sobue K."xsd:string
http://purl.uniprot.org/citations/14596909http://purl.uniprot.org/core/author"Konno D."xsd:string
http://purl.uniprot.org/citations/14596909http://purl.uniprot.org/core/author"Maruoka H."xsd:string
http://purl.uniprot.org/citations/14596909http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14596909http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/14596909http://purl.uniprot.org/core/pages"30-34"xsd:string
http://purl.uniprot.org/citations/14596909http://purl.uniprot.org/core/title"MALS is a binding partner of IRSp53 at cell-cell contacts."xsd:string
http://purl.uniprot.org/citations/14596909http://purl.uniprot.org/core/volume"554"xsd:string
http://purl.uniprot.org/citations/14596909http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/14596909
http://purl.uniprot.org/citations/14596909http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/14596909
http://purl.uniprot.org/uniprot/Q6GMN2#attribution-65DDD1B11A230DBEE0E3B0AABAC19DD6http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/14596909
http://purl.uniprot.org/uniprot/Q9Z252#attribution-65DDD1B11A230DBEE0E3B0AABAC19DD6http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/14596909
http://purl.uniprot.org/uniprot/#_A0A8I6A2M9-mappedCitation-14596909http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14596909
http://purl.uniprot.org/uniprot/#_A0A8I6GJY9-mappedCitation-14596909http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14596909
http://purl.uniprot.org/uniprot/#_A0A8I6AD66-mappedCitation-14596909http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14596909
http://purl.uniprot.org/uniprot/#_B4DMV0-mappedCitation-14596909http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14596909
http://purl.uniprot.org/uniprot/#_B4DQ43-mappedCitation-14596909http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14596909
http://purl.uniprot.org/uniprot/#_B4DWA1-mappedCitation-14596909http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14596909
http://purl.uniprot.org/uniprot/#_B3KPV9-mappedCitation-14596909http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14596909
http://purl.uniprot.org/uniprot/#_O88382-mappedCitation-14596909http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14596909
http://purl.uniprot.org/uniprot/#_Q62696-mappedCitation-14596909http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14596909