http://purl.uniprot.org/citations/14596909 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14596909 | http://www.w3.org/2000/01/rdf-schema#comment | "Insulin receptor substrate p53 (IRSp53) is a key player in cytoskeletal dynamics, interacting with the actin modulators WAVE2 and Mena. Here, we identified a PDZ protein, MALS, as an IRSp53-interacting protein using a yeast two-hybrid screen. A pull-down assay showed that IRSp53 and MALS interact through the PDZ domain of MALS and the C-terminal PDZ-binding sequence of IRSp53. Their interaction in MDCK cells was also demonstrated by co-immunoprecipitation. Immunocytochemistry showed the colocalization of IRSp53 and MALS at cell-cell contacts. Cytochalasin D induced the redistribution of both proteins to the cytosol. Thus, MALS is a partner of IRSp53 anchoring the actin-based membrane cytoskeleton at cell-cell contacts."xsd:string |
http://purl.uniprot.org/citations/14596909 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(03)01074-3"xsd:string |
http://purl.uniprot.org/citations/14596909 | http://purl.uniprot.org/core/author | "Hori K."xsd:string |
http://purl.uniprot.org/citations/14596909 | http://purl.uniprot.org/core/author | "Sobue K."xsd:string |
http://purl.uniprot.org/citations/14596909 | http://purl.uniprot.org/core/author | "Konno D."xsd:string |
http://purl.uniprot.org/citations/14596909 | http://purl.uniprot.org/core/author | "Maruoka H."xsd:string |
http://purl.uniprot.org/citations/14596909 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/14596909 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/14596909 | http://purl.uniprot.org/core/pages | "30-34"xsd:string |
http://purl.uniprot.org/citations/14596909 | http://purl.uniprot.org/core/title | "MALS is a binding partner of IRSp53 at cell-cell contacts."xsd:string |
http://purl.uniprot.org/citations/14596909 | http://purl.uniprot.org/core/volume | "554"xsd:string |
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http://purl.uniprot.org/citations/14596909 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14596909 |
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http://purl.uniprot.org/uniprot/#_B4DQ43-mappedCitation-14596909 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14596909 |
http://purl.uniprot.org/uniprot/#_B4DWA1-mappedCitation-14596909 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14596909 |
http://purl.uniprot.org/uniprot/#_B3KPV9-mappedCitation-14596909 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14596909 |
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