DESCRIBE <http://purl.uniprot.org/citations/14599866>

Subject	Predicate	Object
http://purl.uniprot.org/citations/14599866	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14599866	http://www.w3.org/2000/01/rdf-schema#comment	" Objectives The objective was to investigate the expression of interferon regulatory factors 1 (IRF-1) in human uterine endometrial carcinoma. Methods Formalin-fixed, paraffin-embedded, archival tissue specimens from 76 human endometrial carcinomas and stained with polyclonal anti-IRF-1 antibody, using immunohistochemistry, localization, and immunostaining, were evaluated quantitatively using the H score together with 30 normal endometrium and 16 postmenopausal endometrium. Results The expression of IRF-1 was highest in normal endometrium, and decreased with the grade of endometrioid adenocarcinoma from grade 1 to grade 3. Postmenopausal endometrium was virtually unstained. Conclusions Expression of IRF-1 is altered in human endometrioid adenocarcinoma compared with normal endometrium and postmenopausal endometrium. The loss of IRF-1 expression does not contradict with the tumor-suppressor function. The intensity of IRF-1 expression in each grade of endometrioid adenocarcinoma could be useful prognostic and therapeutic indicators."xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.org/dc/terms/identifier	"doi:10.1016/s0090-8258(03)00515-8"xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/author	"Nakayama T."xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/author	"Okubo T."xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/author	"Fushiki S."xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/author	"Honjo H."xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/author	"Kitaya K."xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/author	"Kuroboshi H."xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/author	"Daikoku N."xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/date	"2003"xsd:gYear
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/name	"Gynecol Oncol"xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/pages	"354-358"xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/title	"Interferon regulatory factor-1 expression in human uterine endometrial carcinoma."xsd:string
http://purl.uniprot.org/citations/14599866	http://purl.uniprot.org/core/volume	"91"xsd:string
http://purl.uniprot.org/citations/14599866	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/14599866
http://purl.uniprot.org/citations/14599866	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/14599866
http://purl.uniprot.org/uniprot/#_A0A0B6XK53-mappedCitation-14599866	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/14599866
http://purl.uniprot.org/uniprot/#_A0A0B6XK11-mappedCitation-14599866	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/14599866
http://purl.uniprot.org/uniprot/#_A0A1B1RS94-mappedCitation-14599866	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/14599866
http://purl.uniprot.org/uniprot/#_A0A510GDD8-mappedCitation-14599866	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/14599866
http://purl.uniprot.org/uniprot/#_B4DQF0-mappedCitation-14599866	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/14599866
http://purl.uniprot.org/uniprot/#_P10914-mappedCitation-14599866	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/14599866
http://purl.uniprot.org/uniprot/#_Q59F37-mappedCitation-14599866	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/14599866
http://purl.uniprot.org/uniprot/#_Q75MZ8-mappedCitation-14599866	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/14599866