http://purl.uniprot.org/citations/14605208 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14605208 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14605208 | http://www.w3.org/2000/01/rdf-schema#comment | "Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence was developed to refine this draft map to a higher confidence map of 4679 proteins and 4780 interactions. Statistical modeling of the network showed two levels of organization: a short-range organization, presumably corresponding to multiprotein complexes, and a more global organization, presumably corresponding to intercomplex connections. The network recapitulated known pathways, extended pathways, and uncovered previously unknown pathway components. This map serves as a starting point for a systems biology modeling of multicellular organisms, including humans."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1090289"xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1090289"xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Williams J."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Williams J."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Zhong J."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Zhong J."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Voss E."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Voss E."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Jarvie T."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Jarvie T."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Kong Y."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Kong Y."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Chaudhuri A."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Chaudhuri A."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "White K.P."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "White K.P."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Burgess S."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Burgess S."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Knight J."xsd:string |
http://purl.uniprot.org/citations/14605208 | http://purl.uniprot.org/core/author | "Knight J."xsd:string |