http://purl.uniprot.org/citations/1461282 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1461282 | http://www.w3.org/2000/01/rdf-schema#comment | "Dystrophin is associated with a complex of muscle membrane (sarcolemmal) glycoproteins that provide a linkage to the extracellular matrix protein, laminin. The absence of dystrophin leads to a dramatic reduction of the dystrophin-associated proteins (156DAG, 59DAP, 50DAG, 43DAG and 35DAG) in the sarcolemma of patients with Duchenne muscular dystrophy and mdx mice. Here we demonstrate that dystrophin-related protein (DRP, utrophin), an autosomal homologue of dystrophin, is associated with an identical or antigenically similar complex of sarcolemmal proteins and that DRP and the dystrophin/DRP-associated proteins colocalize to the neuromuscular junction in Duchenne muscular dystrophy and mdx muscle. The DRP and dystrophin/DRP-associated proteins are found throughout the sarcolemma in small-calibre skeletal muscles and cardiac muscle of adult mdx mice. Because these muscles show minimal pathological changes, our results could provide a basis for the upregulation of DRP as a potential therapeutic approach."xsd:string |
http://purl.uniprot.org/citations/1461282 | http://purl.org/dc/terms/identifier | "doi:10.1038/360588a0"xsd:string |
http://purl.uniprot.org/citations/1461282 | http://purl.uniprot.org/core/author | "Matsumura K."xsd:string |
http://purl.uniprot.org/citations/1461282 | http://purl.uniprot.org/core/author | "Campbell K.P."xsd:string |
http://purl.uniprot.org/citations/1461282 | http://purl.uniprot.org/core/author | "Kahl S.D."xsd:string |
http://purl.uniprot.org/citations/1461282 | http://purl.uniprot.org/core/author | "Ervasti J.M."xsd:string |
http://purl.uniprot.org/citations/1461282 | http://purl.uniprot.org/core/author | "Ohlendieck K."xsd:string |
http://purl.uniprot.org/citations/1461282 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1461282 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
http://purl.uniprot.org/citations/1461282 | http://purl.uniprot.org/core/pages | "588-591"xsd:string |
http://purl.uniprot.org/citations/1461282 | http://purl.uniprot.org/core/title | "Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle."xsd:string |
http://purl.uniprot.org/citations/1461282 | http://purl.uniprot.org/core/volume | "360"xsd:string |
http://purl.uniprot.org/citations/1461282 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1461282 |
http://purl.uniprot.org/citations/1461282 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1461282 |
http://purl.uniprot.org/uniprot/Q810I5#attribution-33C1E2174A6BD444F3786E931A2EE006 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1461282 |
http://purl.uniprot.org/uniprot/Q810I5#attribution-A44098FE650D577C3CAE232F592A57E5 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1461282 |
http://purl.uniprot.org/uniprot/Q3UYS4#attribution-33C1E2174A6BD444F3786E931A2EE006 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1461282 |
http://purl.uniprot.org/uniprot/Q3UYS4#attribution-A44098FE650D577C3CAE232F592A57E5 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1461282 |
http://purl.uniprot.org/uniprot/A0A1W2P6H3#attribution-33C1E2174A6BD444F3786E931A2EE006 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1461282 |
http://purl.uniprot.org/uniprot/A0A1W2P6H3#attribution-A44098FE650D577C3CAE232F592A57E5 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1461282 |
http://purl.uniprot.org/uniprot/Q6P6L2#attribution-33C1E2174A6BD444F3786E931A2EE006 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1461282 |
http://purl.uniprot.org/uniprot/Q6P6L2#attribution-A44098FE650D577C3CAE232F592A57E5 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1461282 |
http://purl.uniprot.org/uniprot/Q3TR59#attribution-33C1E2174A6BD444F3786E931A2EE006 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1461282 |
http://purl.uniprot.org/uniprot/Q3TR59#attribution-A44098FE650D577C3CAE232F592A57E5 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1461282 |