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http://purl.uniprot.org/citations/1461282http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1461282http://www.w3.org/2000/01/rdf-schema#comment"Dystrophin is associated with a complex of muscle membrane (sarcolemmal) glycoproteins that provide a linkage to the extracellular matrix protein, laminin. The absence of dystrophin leads to a dramatic reduction of the dystrophin-associated proteins (156DAG, 59DAP, 50DAG, 43DAG and 35DAG) in the sarcolemma of patients with Duchenne muscular dystrophy and mdx mice. Here we demonstrate that dystrophin-related protein (DRP, utrophin), an autosomal homologue of dystrophin, is associated with an identical or antigenically similar complex of sarcolemmal proteins and that DRP and the dystrophin/DRP-associated proteins colocalize to the neuromuscular junction in Duchenne muscular dystrophy and mdx muscle. The DRP and dystrophin/DRP-associated proteins are found throughout the sarcolemma in small-calibre skeletal muscles and cardiac muscle of adult mdx mice. Because these muscles show minimal pathological changes, our results could provide a basis for the upregulation of DRP as a potential therapeutic approach."xsd:string
http://purl.uniprot.org/citations/1461282http://purl.org/dc/terms/identifier"doi:10.1038/360588a0"xsd:string
http://purl.uniprot.org/citations/1461282http://purl.uniprot.org/core/author"Matsumura K."xsd:string
http://purl.uniprot.org/citations/1461282http://purl.uniprot.org/core/author"Campbell K.P."xsd:string
http://purl.uniprot.org/citations/1461282http://purl.uniprot.org/core/author"Kahl S.D."xsd:string
http://purl.uniprot.org/citations/1461282http://purl.uniprot.org/core/author"Ervasti J.M."xsd:string
http://purl.uniprot.org/citations/1461282http://purl.uniprot.org/core/author"Ohlendieck K."xsd:string
http://purl.uniprot.org/citations/1461282http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1461282http://purl.uniprot.org/core/name"Nature"xsd:string
http://purl.uniprot.org/citations/1461282http://purl.uniprot.org/core/pages"588-591"xsd:string
http://purl.uniprot.org/citations/1461282http://purl.uniprot.org/core/title"Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle."xsd:string
http://purl.uniprot.org/citations/1461282http://purl.uniprot.org/core/volume"360"xsd:string
http://purl.uniprot.org/citations/1461282http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1461282
http://purl.uniprot.org/citations/1461282http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1461282
http://purl.uniprot.org/uniprot/Q810I5#attribution-33C1E2174A6BD444F3786E931A2EE006http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1461282
http://purl.uniprot.org/uniprot/Q810I5#attribution-A44098FE650D577C3CAE232F592A57E5http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1461282
http://purl.uniprot.org/uniprot/Q3UYS4#attribution-33C1E2174A6BD444F3786E931A2EE006http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1461282
http://purl.uniprot.org/uniprot/Q3UYS4#attribution-A44098FE650D577C3CAE232F592A57E5http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1461282
http://purl.uniprot.org/uniprot/A0A1W2P6H3#attribution-33C1E2174A6BD444F3786E931A2EE006http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1461282
http://purl.uniprot.org/uniprot/A0A1W2P6H3#attribution-A44098FE650D577C3CAE232F592A57E5http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1461282
http://purl.uniprot.org/uniprot/Q6P6L2#attribution-33C1E2174A6BD444F3786E931A2EE006http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1461282
http://purl.uniprot.org/uniprot/Q6P6L2#attribution-A44098FE650D577C3CAE232F592A57E5http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1461282
http://purl.uniprot.org/uniprot/Q3TR59#attribution-33C1E2174A6BD444F3786E931A2EE006http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1461282
http://purl.uniprot.org/uniprot/Q3TR59#attribution-A44098FE650D577C3CAE232F592A57E5http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1461282