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http://purl.uniprot.org/citations/14627435 | http://www.w3.org/2000/01/rdf-schema#comment | "The inhibition of glucokinase by rat and Xenopus GKRPs (glucokinase regulatory protein) is well documented. We report a comparison of the effects of human and rat GKRPs on glucokinase activity. Human GKRP is a more potent inhibitor of glucokinase than rat GKRP in the absence of fructose 6-phosphate or sorbitol 6-phosphate, and has a higher affinity for these ligands. However, human and rat GKRPs have similar affinities for fructose 1-phosphate and chloride. Residues that are not conserved between the rodent and human proteins affect both the affinity for fructose 6-phosphate and sorbitol 6-phosphate and the inhibitory potency of GKRP on glucokinase in the absence of these ligands."xsd:string |
http://purl.uniprot.org/citations/14627435 | http://purl.org/dc/terms/identifier | "doi:10.1042/bj20031414"xsd:string |
http://purl.uniprot.org/citations/14627435 | http://purl.uniprot.org/core/author | "Davies R.A."xsd:string |
http://purl.uniprot.org/citations/14627435 | http://purl.uniprot.org/core/author | "Brocklehurst K.J."xsd:string |
http://purl.uniprot.org/citations/14627435 | http://purl.uniprot.org/core/author | "Agius L."xsd:string |
http://purl.uniprot.org/citations/14627435 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/14627435 | http://purl.uniprot.org/core/name | "Biochem J"xsd:string |
http://purl.uniprot.org/citations/14627435 | http://purl.uniprot.org/core/pages | "693-697"xsd:string |
http://purl.uniprot.org/citations/14627435 | http://purl.uniprot.org/core/title | "Differences in regulatory properties between human and rat glucokinase regulatory protein."xsd:string |
http://purl.uniprot.org/citations/14627435 | http://purl.uniprot.org/core/volume | "378"xsd:string |
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