| http://purl.uniprot.org/citations/14644028 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14644028 | http://www.w3.org/2000/01/rdf-schema#comment | "CCR5 is expressed in neurons but its function in this cellular context is hitherto poorly understood. We have generated CCR5-expressing SH-SY5Y neuroblastoma cells. CCR5 ligands induced cell death in these cells, but not in control neuroblastoma cells or in CCR5-expressing fibroblasts. CCR5-dependent killing of neuroblastoma cells occurred through apoptosis, since it was accompanied by caspase-3 activation and could be prevented by a caspase-3 inhibitor. Finally, cell killing by activated microglia was more rapid and extensive in CCR5-expressing neuroblastoma cells than in control cells. In summary, CCR5 may act as a death receptor in cells of neuronal lineage and therefore be involved in inflammatory neurodegeneration."xsd:string |
| http://purl.uniprot.org/citations/14644028 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jneuroim.2003.09.008"xsd:string |
| http://purl.uniprot.org/citations/14644028 | http://purl.uniprot.org/core/author | "Hartley O."xsd:string |
| http://purl.uniprot.org/citations/14644028 | http://purl.uniprot.org/core/author | "Irminger-Finger I."xsd:string |
| http://purl.uniprot.org/citations/14644028 | http://purl.uniprot.org/core/author | "Krause K.H."xsd:string |
| http://purl.uniprot.org/citations/14644028 | http://purl.uniprot.org/core/author | "Cartier L."xsd:string |
| http://purl.uniprot.org/citations/14644028 | http://purl.uniprot.org/core/author | "Dubois-Dauphin M."xsd:string |
| http://purl.uniprot.org/citations/14644028 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14644028 | http://purl.uniprot.org/core/name | "J Neuroimmunol"xsd:string |
| http://purl.uniprot.org/citations/14644028 | http://purl.uniprot.org/core/pages | "27-39"xsd:string |
| http://purl.uniprot.org/citations/14644028 | http://purl.uniprot.org/core/title | "Chemokine-induced cell death in CCR5-expressing neuroblastoma cells."xsd:string |
| http://purl.uniprot.org/citations/14644028 | http://purl.uniprot.org/core/volume | "145"xsd:string |
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