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http://purl.uniprot.org/citations/14647991http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14647991http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14647991http://www.w3.org/2000/01/rdf-schema#comment"With the human and mouse genome projects now completed, the receptor repertoire of mammalian cells has finally been elucidated. The EGF-TM7 receptors are a family of class B seven-span transmembrane (TM7) receptors predominantly expressed by cells of the immune system. Within the large TM7 superfamily, the molecular structure and ligand-binding properties of EGF-TM7 receptors are unique. Derived from the processing of a single polypeptide, they are expressed at the cell surface as heterodimers consisting of a large extracellular region associated with a TM7 moiety. Through a variable number of N-terminal epidermal growth factor (EGF)-like domains, EGF-TM7 receptors interact with cellular ligands such as CD55 and chondroitin sulfate. Recent in vivo studies demonstrate a role of the EGF-TM7 receptor CD97 in leukocyte migration. The different number of EGF-TM7 genes in man compared with mice, the chimeric nature of EMR2 and the inactivation of human EMR4 point toward a still-evolving receptor family. Here we discuss the currently available information on this intriguing receptor family."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.org/dc/terms/identifier"doi:10.1007/s00251-003-0625-2"xsd:string
http://purl.uniprot.org/citations/14647991http://purl.org/dc/terms/identifier"doi:10.1007/s00251-003-0625-2"xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Lin H.H."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Lin H.H."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Gordon S."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Gordon S."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Hamann J."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Hamann J."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Kop E.N."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Kop E.N."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Kwakkenbos M.J."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Kwakkenbos M.J."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Matmati M."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Matmati M."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Stacey M."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/author"Stacey M."xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/name"Immunogenetics"xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/name"Immunogenetics"xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/pages"655-666"xsd:string
http://purl.uniprot.org/citations/14647991http://purl.uniprot.org/core/pages"655-666"xsd:string