| http://purl.uniprot.org/citations/14662740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14662740 | http://www.w3.org/2000/01/rdf-schema#comment | "Condensin is an evolutionarily conserved protein complex that helps mediate chromosome condensation and segregation in mitotic cells. Here, we show that condensin has two activities that contribute to meiotic chromosome condensation in Saccharomyces cerevisiae. One activity, common to mitosis, helps mediate axial length compaction. A second activity promotes chromosome individualization with the help of Red1 and Hop1, two meiotic specific components of axial elements. Like Red1 and Hop1, condensin is also required for efficient homologue pairing and proper processing of double strand breaks. Consistent with these functional links condensin is necessary for proper chromosomal localization of Red1 and Hop1 and the subsequent assembly of the synaptonemal complex. Finally, condensin has a Red1/Hop1-independent role in the resolution of recombination-dependent linkages between homologues in meiosis I. The existence of distinct meiotic activities of condensin (axial compaction, individualization, and resolution of recombination-dependent links) provides an important framework to understand condensin's role in both meiotic and mitotic chromosome structure and function."xsd:string |
| http://purl.uniprot.org/citations/14662740 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200308027"xsd:string |
| http://purl.uniprot.org/citations/14662740 | http://purl.uniprot.org/core/author | "Yu H.G."xsd:string |
| http://purl.uniprot.org/citations/14662740 | http://purl.uniprot.org/core/author | "Koshland D.E."xsd:string |
| http://purl.uniprot.org/citations/14662740 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14662740 | http://purl.uniprot.org/core/name | "J Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/14662740 | http://purl.uniprot.org/core/pages | "937-947"xsd:string |
| http://purl.uniprot.org/citations/14662740 | http://purl.uniprot.org/core/title | "Meiotic condensin is required for proper chromosome compaction, SC assembly, and resolution of recombination-dependent chromosome linkages."xsd:string |
| http://purl.uniprot.org/citations/14662740 | http://purl.uniprot.org/core/volume | "163"xsd:string |
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