Results

RDF/XMLNTriplesTurtleShow queryShare ▶
SubjectPredicateObject
http://purl.uniprot.org/citations/14674935http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14674935http://www.w3.org/2000/01/rdf-schema#comment"

Background

Toluene diisocyanate (TDI)-induced asthma is a common cause of occupational asthma and it affects 5-15% of the exposed population suggesting an underlying genetic susceptibility.

Methods

To investigate the role of genetic factors in the development of TDI-induced asthma, we analyzed the distribution of human leukocyte antigen (HLA) class I genes and of tumor necrosis factor (TNF)-alpha A-308G polymorphism in 142 patients with TDI-induced asthma and in 50 asymptomatic exposed subjects.

Results

Neither the distribution of HLA class I antigens nor the distribution of TNF-alpha A-308G polymorphism was different between patients with TDI-induced asthma and asymptomatic exposed subjects.

Conclusions

These results suggest that HLA class I antigens and TNF-alpha A-308G are not associated with susceptibility or resistance to the development of TDI-induced asthma."xsd:string
http://purl.uniprot.org/citations/14674935http://purl.org/dc/terms/identifier"doi:10.1046/j.1398-9995.2003.00352.x"xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/author"Holgate S.T."xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/author"Holloway J.W."xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/author"Howell W.M."xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/author"Mapp C.E."xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/author"Padoan M."xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/author"Beghe B."xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/author"Barton S.J."xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/author"Moss C.T."xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/name"Allergy"xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/pages"61-64"xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/title"Lack of association of HLA class I genes and TNF alpha-308 polymorphism in toluene diisocyanate-induced asthma."xsd:string
http://purl.uniprot.org/citations/14674935http://purl.uniprot.org/core/volume"59"xsd:string
http://purl.uniprot.org/citations/14674935http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/14674935
http://purl.uniprot.org/citations/14674935http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/14674935
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-14674935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14674935
http://purl.uniprot.org/uniprot/#_A0A0A7C549-mappedCitation-14674935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14674935
http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-14674935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14674935
http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-14674935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14674935
http://purl.uniprot.org/uniprot/#_A0A0A7C553-mappedCitation-14674935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14674935
http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-14674935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14674935
http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-14674935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14674935
▶