| http://purl.uniprot.org/citations/1468569 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1468569 | http://www.w3.org/2000/01/rdf-schema#comment | "Here we report that bone morphogenetic proteins 2 and 3 (BMP-2 and BMP-3) induced marked expression of c-fos mRNA in a biphasic manner, i.e. the late phase (48 to 60 h) as well as the immediate-early phase (0.5 h), in murine osteoblastic MC3T3-E1 cells in vitro. The BMP-induced late phase c-fos gene expression was temporally associated with the onset of marked expression of the genes for osteocalcin and alkaline phosphatase, differentiation markers of mature osteoblasts. In contrast, none of TGF-beta 1, 10% FBS, IGF-I and IGF-II, which induced only the immediate-early c-fos mRNA expression, stimulated the expression of osteocalcin and alkaline phosphatase genes. These data suggest that in osteoblasts BMP-2 and BMP-3 induce the late phase expression of c-fos, which may play a role in transcriptional activation of the genes involved in differentiation of osteoblasts."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.org/dc/terms/identifier | "doi:10.1016/0014-5793(92)81505-g"xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/author | "Kikuchi H."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/author | "Konishi J."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/author | "Lee K."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/author | "Ikeda T."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/author | "Kohno H."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/author | "Ohta S."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/author | "Suzuki F."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/author | "Hiraki Y."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/author | "Shigeno C."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/author | "Kasai R."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/pages | "356-360"xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/title | "Bone morphogenetic proteins (BMP-2 and BMP-3) induce the late phase expression of the proto-oncogene c-fos in murine osteoblastic MC3T3-E1 cells."xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/volume | "314"xsd:string |
| http://purl.uniprot.org/citations/1468569 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1468569 |
| http://purl.uniprot.org/citations/1468569 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1468569 |
| http://purl.uniprot.org/citations/1468569 | http://purl.uniprot.org/core/authorsIncomplete | "true"xsd:boolean |
| http://purl.uniprot.org/uniprot/Q8BHE5#attribution-8009D4C3BECED5C807F4134B14354F57 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1468569 |
| http://purl.uniprot.org/uniprot/P21274#attribution-8009D4C3BECED5C807F4134B14354F57 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1468569 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JE75-mappedCitation-1468569 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1468569 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JEU2-mappedCitation-1468569 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1468569 |