http://purl.uniprot.org/citations/14688323 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14688323 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14688323 | http://www.w3.org/2000/01/rdf-schema#comment | "The NF-AT family is a group of potent transcription factors that are essential for T cell activation in vitro. However, NF-ATc2-deficient Th cells display hyperproliferation in response to stimulation, suggesting that NF-ATc2 functions as a negative regulator of Th cell activation/proliferation. In this study we show that the transcriptional repressor of GATA (ROG) is a direct target gene of NF-ATc2 and that NF-ATc2-deficient Th cells are unable to fully up-regulate ROG upon stimulation. Restoration of ROG expression in vivo partly corrects the hyperproliferation of NF-ATc2-deficient Th cells by attenuating TCR signals. Our data, therefore, depict a ROG-mediated negative feedback mechanism of T cell activation."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.172.1.170"xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/author | "Kang B.Y."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/author | "Kang B.Y."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/author | "Ho I.C."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/author | "Ho I.C."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/author | "Miaw S.C."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/author | "Miaw S.C."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/author | "White I.A."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/author | "White I.A."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/pages | "170-177"xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/pages | "170-177"xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/title | "A repressor of GATA-mediated negative feedback mechanism of T cell activation."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/title | "A repressor of GATA-mediated negative feedback mechanism of T cell activation."xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/volume | "172"xsd:string |
http://purl.uniprot.org/citations/14688323 | http://purl.uniprot.org/core/volume | "172"xsd:string |
http://purl.uniprot.org/citations/14688323 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14688323 |
http://purl.uniprot.org/citations/14688323 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14688323 |
http://purl.uniprot.org/citations/14688323 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14688323 |