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http://purl.uniprot.org/citations/14690248http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14690248http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14690248http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Citation
http://purl.uniprot.org/citations/14690248http://www.w3.org/2000/01/rdf-schema#comment"Ethanol oxidation by nicotinoprotein alcohol dehydrogenase (np-ADH) from the bacterium Amycolatopsis methanolica is inhibited by trans-4-(N,N-dimethylamino)-cinnamaldehyde through direct binding to the catalytic zinc ion in a substrate-like geometry. This binding is accompanied by a characteristic red shift of the aldehyde absorbance from 398 nm to 467 nm. Np-ADH is structurally related to mammalian ADH class I, and a model of np-ADH shows how the cinnamaldehyde derivative can be accommodated in the active site of the nicotinoprotein, correlating the structural and enzymological data."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.org/dc/terms/identifier"doi:10.1023/b:jopc.0000005461.53788.ee"xsd:string
http://purl.uniprot.org/citations/14690248http://purl.org/dc/terms/identifier"doi:10.1023/b:jopc.0000005461.53788.ee"xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/author"Duine J.A."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/author"Duine J.A."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/author"Jornvall H."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/author"Jornvall H."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/author"de Vries S."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/author"de Vries S."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/author"Norin A."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/author"Norin A."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/author"Piersma S.R."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/author"Piersma S.R."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/name"J. Protein Chem."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/name"J. Protein Chem."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/pages"457-461"xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/pages"457-461"xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/title"Inhibition of nicotinoprotein (NAD+-containing) alcohol dehydrogenase by trans-4-(N,N-dimethylamino)-cinnamaldehyde binding to the active site."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/title"Inhibition of nicotinoprotein (NAD+-containing) alcohol dehydrogenase by trans-4-(N,N-dimethylamino)-cinnamaldehyde binding to the active site."xsd:string
http://purl.uniprot.org/citations/14690248http://purl.uniprot.org/core/volume"22"xsd:string